Hemorrhoid

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Hemorrhoids
Other namesHaemorrhoids, piles,
NSAIDs, rest, surgery[1][6]
Frequency50–66% at some time[1][3]

Hemorrhoids (or haemorrhoids), also known as piles, are

swollen or inflamed; the unqualified term hemorrhoid is often used to refer to the disease.[8] The signs and symptoms of hemorrhoids depend on the type present.[4] Internal hemorrhoids often result in painless, bright red rectal bleeding when defecating.[3][4] External hemorrhoids often result in pain and swelling in the area of the anus.[4] If bleeding occurs, it is usually darker.[4] Symptoms frequently get better after a few days.[3] A skin tag may remain after the healing of an external hemorrhoid.[4]

While the exact cause of hemorrhoids remains unknown, a number of factors that increase pressure in the abdomen are believed to be involved.[4] This may include constipation, diarrhea, and sitting on the toilet for long periods.[3] Hemorrhoids are also more common during pregnancy.[3] Diagnosis is made by looking at the area.[3] Many people incorrectly refer to any symptom occurring around the anal area as hemorrhoids, and serious causes of the symptoms should not be ruled out.[2] Colonoscopy or sigmoidoscopy is reasonable to confirm the diagnosis and rule out more serious causes.[9]

Often, no specific treatment is needed.[9] Initial measures consist of increasing fiber intake, drinking fluids to maintain hydration, NSAIDs to help with pain, and rest.[1] Medicated creams may be applied to the area, but their effectiveness is poorly supported by evidence.[9] A number of minor procedures may be performed if symptoms are severe or do not improve with conservative management.[6] Surgery is reserved for those who fail to improve following these measures.[6]

Approximately 50% to 66% of people have problems with hemorrhoids at some point in their lives.[1][3] Males and females are both affected with about equal frequency.[1] Hemorrhoids affect people most often between 45 and 65 years of age,[5] and they are more common among the wealthy.[4] Outcomes are usually good.[3][9]

The first known mention of the disease is from a 1700 BC Egyptian papyrus.[10]

Signs and symptoms

An external hemorrhoid

In about 40% of people with pathological hemorrhoids, there are no significant symptoms.[4] Internal and external hemorrhoids may present differently; however, many people may have a combination of the two.[8] Bleeding enough to cause anemia is rare,[5] and life-threatening bleeding is even more uncommon.[11] Many people feel embarrassed when facing the problem[5] and often seek medical care only when the case is advanced.[8]

External

If not

skin tag may remain after healing.[8] If hemorrhoids are large and cause issues with hygiene, they may produce irritation of the surrounding skin, and thus itchiness around the anus.[12]

Lidocaine is a local anesthetic that blocks the transmission of nerve messages before reaching the central nervous system by blocking the calcium channel. As a result, the patient does not feel any pain. In addition, this drug is anti-inflammatory and is effective in treating hemorrhoids.[dubious – discuss][13] Lidocaine is not recommended if you are pregnant or have a local allergy.

Internal

Internal hemorrhoids usually present with painless, bright red rectal bleeding during or following a bowel movement.[8] The blood typically covers the stool (a condition known as hematochezia), is on the toilet paper, or drips into the toilet bowl.[8] The stool itself is usually normally coloured.[8] Other symptoms may include mucous discharge, a perianal mass if they prolapse through the anus, itchiness, and fecal incontinence.[11][14] Internal hemorrhoids are usually painful only if they become thrombosed or necrotic.[8]

Causes

The exact cause of symptomatic hemorrhoids is unknown.[15] A number of factors are believed to play a role, including irregular bowel habits (constipation or diarrhea), lack of exercise, nutritional factors (low-fiber diets), increased intra-abdominal pressure (prolonged straining, ascites, an intra-abdominal mass, or pregnancy), genetics, an absence of valves within the hemorrhoidal veins, and aging.[1][5] Other factors believed to increase risk include obesity, prolonged sitting,[8][dubious – discuss] a chronic cough, and pelvic floor dysfunction.[2] Squatting while defecating may also increase the risk of severe hemorrhoids.[16] Evidence for these associations, however, is poor.[2] Being a receptive partner in anal intercourse has been listed as a cause.[17][18][19]

During pregnancy, pressure from the fetus on the abdomen and hormonal changes cause the hemorrhoidal vessels to enlarge. The birth of the baby also leads to increased intra-abdominal pressures.[20] Pregnant women rarely need surgical treatment, as symptoms usually resolve after delivery.[1]

Pathophysiology

Gross pathology of hemorrhoids, showing engorged blood vessels

Hemorrhoid cushions are a part of normal human anatomy and become a pathological disease only when they experience abnormal changes.

hemorrhoidal plexus.[2]

Hemorrhoid cushions are important for

superior hemorrhoidal plexus and externals from the inferior hemorrhoidal plexus.[5] The pectinate line divides the two regions.[5]

Diagnosis

Internal hemorrhoid grades
Grade Diagram Picture
1 Endoscopic view
2
3
4

Hemorrhoids are typically diagnosed by physical examination.

tumors, polyps, an enlarged prostate, or abscesses.[8] This examination may not be possible without appropriate sedation because of pain, although most internal hemorrhoids are not associated with pain.[1] If pain is present, the condition is more likely to be an anal fissure or external hemorrhoid rather than internal hemorrhoid.[5]

Internal

Internal hemorrhoids originate above the pectinate line.

receptors.[2] They were classified in 1985 into four grades based on the degree of prolapse:[1][2]

External

A thrombosed external hemorrhoid

anoderm and distally by skin, both of which are sensitive to pain and temperature.[2]

Differential

Many anorectal problems, including fissures, fistulae, abscesses, colorectal cancer, rectal varices, and itching have similar symptoms and may be incorrectly referred to as hemorrhoids.[1] Rectal bleeding may also occur owing to colorectal cancer, colitis including inflammatory bowel disease, diverticular disease, and angiodysplasia.[6] If anemia is present, other potential causes should be considered.[5]

Other conditions that produce an anal mass include

anal warts, rectal prolapse, polyps, and enlarged anal papillae.[5] Anorectal varices due to portal hypertension (blood pressure in the portal venous system) may present similar to hemorrhoids but are a different condition.[5] Portal hypertension does not increase the risk of hemorrhoids.[4]

Prevention

A number of preventative measures are recommended, including avoiding straining while attempting to defecate, avoiding constipation and diarrhea either by eating a high-fiber diet and drinking plenty of fluid or by taking fiber supplements and getting sufficient exercise.

defecate, avoiding reading while on the toilet,[1] and losing weight for overweight persons and avoiding heavy lifting are also recommended.[22]

Management

Conservative

Conservative treatment typically consists of foods rich in dietary fiber, intake of oral fluids to maintain hydration, nonsteroidal anti-inflammatory drugs, sitz baths, and rest.[1] Increased fiber intake has been shown to improve outcomes[23] and may be achieved by dietary alterations or the consumption of fiber supplements.[1][23] Evidence for benefits from sitz baths during any point in treatment, however, is lacking.[24] If they are used, they should be limited to 15 minutes at a time.[2]: 182  Decreasing time spent on the toilet and not straining is also recommended.[25]

While many

epinephrine.[2] Some contain Balsam of Peru to which certain people may be allergic.[27][28]

Flavonoids are of questionable benefit, with potential side effects.[2][29] Symptoms usually resolve following pregnancy; thus active treatment is often delayed until after delivery.[30] Evidence does not support the use of traditional Chinese herbal treatment.[31]

Several professional organizations[

phlebotonics in the treatment of the symptoms of haemorrhoids grade I to II,[26][32][33][34][35][36][excessive citations] although these drugs are not approved in the United States as of 2013[37] and in Germany,[38] and restricted in Spain for the treatment of chronic venous diseases.[39]

Procedures

A number of office-based procedures may be performed. While generally safe, rare serious side effects such as perianal sepsis may occur.[6]

  1. Rubber band ligation is typically recommended as the first-line treatment in those with grade I to III disease.[6] It is a procedure in which elastic bands are applied onto internal hemorrhoid at least 1 cm above the pectinate line to cut off its blood supply. Within 5–7 days, the withered hemorrhoid falls off. If the band is placed too close to the pectinate line, intense pain results immediately afterwards.[1] The cure rate has been found to be about 87%,[1] with a complication rate of up to 3%.[6]
  2. sclerosing agent, such as phenol, into the hemorrhoid. This causes the vein walls to collapse and the hemorrhoids to shrivel up. The success rate four years after treatment is about 70%.[1]
  3. A number of
    infrared radiation, laser surgery,[1] or cryosurgery.[40] Infrared cauterization may be an option for grade I or II disease.[6] In those with grade III or IV disease, reoccurrence rates are high.[6]

Surgery

A number of surgical techniques may be used if conservative management and simple procedures fail.[6] All surgical treatments are associated with some degree of complications, including bleeding, infection, anal strictures, and urinary retention, due to the close proximity of the rectum to the nerves that supply the bladder.[1] Also, a small risk of fecal incontinence occurs, particularly of liquid,[2][41] with rates reported between 0% and 28%.[42] Mucosal ectropion is another condition which may occur after hemorrhoidectomy (often together with anal stenosis).[43] This is where the anal mucosa becomes everted from the anus, similar to a very mild form of rectal prolapse.[43]

  1. Excisional hemorrhoidectomy is a surgical excision of the hemorrhoid used primarily only in severe cases.
    Glyceryl trinitrate ointment after the procedure helps both with pain and with healing.[45]
  2. Doppler-guided transanal hemorrhoidal dearterialization is a minimally invasive treatment using an ultrasound Doppler to accurately locate the arterial blood inflow. These arteries are then "tied off" and the prolapsed tissue is sutured back to its normal position. It has a slightly higher recurrence rate but fewer complications compared to a hemorrhoidectomy.[1]
  3. Stapled hemorrhoidectomy, also known as stapled hemorrhoidopexy, involves the removal of much of the abnormally enlarged hemorrhoidal tissue, followed by a repositioning of the remaining hemorrhoidal tissue back to its normal anatomical position. It is generally less painful and is associated with faster healing compared to complete removal of hemorrhoids.[1] However, the chance of symptomatic hemorrhoids returning is greater than for conventional hemorrhoidectomy,[46] so it is typically recommended only for grade II or III disease.[6]

Epidemiology

It is difficult to determine how common hemorrhoids are as many people with the condition do not see a healthcare provider.[11][15] However, symptomatic hemorrhoids are thought to affect at least 50% of the US population at some time during their lives, and around 5% of the population is affected at any given time.[1] Both sexes experience about the same incidence of the condition,[1] with rates peaking between 45 and 65 years.[5] They are more common in Caucasians[47] and those of higher socioeconomic status.[2]

Long-term outcomes are generally good, though some people may have recurrent symptomatic episodes.[11] Only a small proportion of persons end up needing surgery.[2]

History

An 11th-century English miniature. On the right is an operation to remove hemorrhoids.

The first known mention of this disease is from a 1700 BC Egyptian

Hippocratic corpus discusses a treatment similar to modern rubber band ligation: "And hemorrhoids in like manner you may treat by transfixing them with a needle and tying them with very thick and woolen thread, for application, and do not foment until they drop off, and always leave one behind; and when the patient recovers, let him be put on a course of Hellebore."[10] Hemorrhoids may have been described in the Bible, with earlier English translations using the now-obsolete spelling "emerods".[5]

Susruta Samhita (4th–5th century BC) is similar to the words of Hippocrates, but emphasizes wound cleanliness.[10] In the 13th century, European surgeons such as Lanfranc of Milan, Guy de Chauliac, Henri de Mondeville, and John of Ardene made great progress and development of the surgical techniques.[48]

In medieval times, hemorrhoids were also known as Saint Fiacre's curse after a sixth-century saint who developed them following tilling the soil.[49] The first use of the word "hemorrhoid" in English occurs in 1398, derived from the Old French "emorroides", from Latin hæmorrhoida,[50] in turn from the Greek αἱμορροΐς (haimorrhois), "liable to discharge blood", from αἷμα (haima), "blood"[51] and ῥόος (rhoos), "stream, flow, current",[52] itself from ῥέω (rheo), "to flow, to stream".[53]

Notable cases

  • Hall-of-Fame baseball player
    George Brett was removed from a game in the 1980 World Series due to hemorrhoid pain. After undergoing minor surgery, Brett returned to play in the next game, quipping, "My problems are all behind me".[54] Brett underwent further hemorrhoid surgery the following spring.[55]
  • Conservative political commentator Glenn Beck underwent surgery for hemorrhoids, subsequently describing his unpleasant experience in a widely viewed 2008 YouTube video.[56][57]
  • Former U.S. President Jimmy Carter had surgery for hemorrhoids in 1984.[58]
  • Cricketers Matthew Hayden and Viv Richards have suffered the condition.[59]
  • During World War II, US Army Lieutenant Colonel Harold Cohen was selected by General George S. Patton to organize a raid to rescue Patton's son-in-law from a German prison camp; Cohen was prevented from leading the raid due to hemorrhoids.[60] Patton personally examined Cohen and remarked, "that is some sorry ass".[61]

References

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External links

Wikimedia Commons has media related to Hemorrhoids.
  • Hemorrhoid at
    Curlie
  • Davis, BR; Lee-Kong, SA; Migaly, J; Feingold, DL; Steele, SR (March 2018). "The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Hemorrhoids". Diseases of the Colon and Rectum. 61 (3): 284–292.
    S2CID 4198610
    .
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