Haplogroup E-M2
Haplogroup E-M2 (former E3a / E1b1a) | |
---|---|
![]() Interpolated frequency distribution.[1] | |
Possible time of origin | 39,200 years BP[2] |
Coalescence age | 16,300 years BP[2] |
Possible place of origin | West Africa[3][4] or Central Africa[3][4] |
Ancestor | E-V38 |
Descendants | E-Z5994, E-V43 |
Defining mutations | M2, DYS271/SY81, M291, P1/PN1, P189.1, P293.1 |
Haplogroup E-M2, also known as E1b1a1-M2, is a human Y-chromosome DNA haplogroup. E-M2 is primarily distributed within Africa followed by West Asia. More specifically, E-M2 is the predominant subclade in West Africa, Central Africa, Southern Africa, and the region of the African Great Lakes; it also occurs at moderate frequencies in North Africa, and the Middle East. E-M2 has several subclades, but many of these subhaplogroups are included in either E-L485 or E-U175. E-M2 is especially common among indigenous Africans who speak Niger-Congo languages, and was spread to Southern Africa and East Africa through the Bantu expansion.
Origins
The discovery of two SNPs (V38 and V100) by Trombetta et al. (2011) significantly redefined the E-V38 phylogenetic tree. This led the authors to suggest that
Ancient DNA
Within Africa
Botswana
At Xaro, in Botswana, there were two individuals, dated to the Early Iron Age (1400 BP); one carried haplogroups E1b1a1a1c1a and L3e1a2, and another carried haplogroups E1b1b1b2b (E-M293, E-CTS10880) and L0k1a2.[13][14]
At Taukome, in Botswana, an individual, dated to the Early Iron Age (1100 BP), carried haplogroups E1b1a1 (E-M2, E-Z1123) and L0d3b1.[13][14]
Democratic Republic of Congo
At Kindoki, in the Democratic Republic of Congo, there were three individuals, dated to the protohistoric period (230 BP, 150 BP, 230 BP); one carried haplogroups E1b1a1a1d1a2 (E-CTS99, E-CTS99) and L1c3a1b, another carried haplogroup E (E-M96, E-PF1620), and the last carried haplogroups R1b1 (R-P25 1, R-M415) and L0a1b1a1.[13][14]
Egypt
Hawass et al. (2012) determined that the ancient Egyptian mummy of an unknown man buried with
Kenya
At Deloraine Farm, in
At Lamu, Pate Island, Faza, in Kenya, an individual, dated between 1500 CE and 1700 CE, carried haplogroups E1b1a1a1a2a1a and L3e3a.[19]
At Taita Taveta, Makwasinyi, in Kenya, an individual, dated between 1650 CE and 1950 CE, carried haplogroups E1b1a1a1a2a1a and L4b2a.[19]
At Taita Taveta, Makwasinyi, in Kenya, an individual, dated between 1650 CE and 1950 CE, carried haplogroups E1b1a1a1a2a1a3b1d1c and L1c3b1a.[19]
At Taita Taveta, Makwasinyi, in Kenya, an individual, dated between 1650 CE and 1950 CE, carried haplogroups E1b1a1a1a2a1a and L2a1+143.[19]
At Taita Taveta, Makwasinyi, in Kenya, an individual, dated between 1667 cal CE and 1843 cal CE, carried haplogroups E1b1a1a1a2a1a3b1d1c and L2a1+143.[19]
At Taita Taveta, Makwasinyi, in Kenya, an individual, dated between 1709 cal CE and 1927 cal CE, carried haplogroups E1b1a1a1a2a1a3a1d~ and L3a2.[19]
Tanzania
At Songo Mnara, in Tanzania, an individual, dated between 1418 cal CE and 1450 cal CE, carried haplogroups E1b1a1~ and L3e2b.[19]
At Lindi, in Tanzania, an individual, dated between 1511 cal CE and 1664 cal CE, carried haplogroups E1b1a1a1a2a1a3a1d~ and L0a1a2.[19]
Outside of Africa
France
At
Mexico
At a San Jose de los Naturales Royal Hospital burial site, in
Portugal
At Cabeço da Amoreira, in Portugal, an
Saint Helena
In
Spain
In
United States of America
At Avery’s Rest, in Chesapeake, Delaware, 3 out of 11 individuals were African Americans, who were dated between 1675 CE and 1725 CE; one was of West African ancestry and carried haplogroups E1b1a-CTS2447 and L3e3b, another was of western Central African Bantu-speaking ancestry and carried E1b1a-Z5974 and L0a1a2, and another was of West African and East African ancestry and carried E1b1a-Z5974 and L3d2.[36]
At Catoctin Furnace African American Cemetery, in Catoctin Furnace, Maryland, there were 27 African Americans found who were dated between 1774 CE and 1850 CE.[37][38] One male individual, who was of 98.14% Sub-Saharan African ancestry, carried haplogroups E1b1a1a1a1c2c and L2a1+143+@16309.[39] One male individual, who was of 83.73% Sub-Saharan African and 7.74% European ancestry, carried haplogroups E1b1a1a1a1c1b1 and L3e2a1b1.[39] One male individual, who was of 84.94% Sub-Saharan African and 9.45% European ancestry, carried haplogroups E1b1a1a1a2a1a and L2a1+143+16189 (16192)+@16309.[39] One male individual, who was of 87.83% Sub-Saharan African and 8.23% European ancestry, carried haplogroups E1b1a1a1a1c1a1a3a1d1 and L3d1b3.[39] One male individual, who was of 98.14% Sub-Saharan African ancestry, carried haplogroups E1b1a1a1a1a and L3e2a1b1.[39] One male individual, who was of 93.87% Sub-Saharan African and 2.58% European ancestry, carried haplogroups E1b1a1a1 and L3e1.[39] One male individual, who was of 98.70% Sub-Saharan African ancestry, carried haplogroups E1b1a1a1a1c1b2a and L2a1a1.[39] One male individual, who was of 97.01% Sub-Saharan African ancestry, carried haplogroups E1b1a1a1a1c1a1 and L3e2a1b1.[39] One male individual, who was of 82.31% Sub-Saharan African and 10.24% European ancestry, carried haplogroups E1b1a1a1a1c1b and L3e2a1b1.[39] One male individual, who was of 91.82% Sub-Saharan African and 5.31% European ancestry, carried haplogroups E1b1a1a1a1c1a1 and L3e2.[39] One male individual, who was of 81.18% Sub-Saharan African and 14.86% European ancestry, carried haplogroups E1b1a1~ and L2c.[39]
At an Anson Street burial site, in
Medical DNA
Sickle Cell
Amid the Green Sahara, the mutation for
Distribution
E-M2's frequency and diversity are highest in West Africa. Within Africa, E-M2 displays a west-to-east as well as a south-to-north clinal distribution. In other words, the frequency of the haplogroup decreases as one moves from western and southern Africa toward the eastern and northern parts of Africa.[45]
Population group | frequency | References |
---|---|---|
Bamileke |
96%-100% | [45][46] |
Ewe | 97% | [11] |
Ga |
97% | [11] |
Hutu | 94.2% | [45] |
Yoruba | 93.1% | [47] |
Tutsi | 85.1% | [45] |
Fante | 84% | [11] |
Mandinka | 79%–83% | [10][11] |
Ovambo | 82% | [11] |
Senegalese | 81% | [48] |
Ganda |
77% | [11] |
Bijagós | 76% | [10] |
Balanta | 73% | [10] |
Fula | 73% | [10] |
Kikuyu | 73% | [11] |
Herero | 71% | [11] |
Nalú | 71% | [10] |
Populations in Northwest Africa, central Eastern Africa and Madagascar have tested at more moderate frequencies.
Population group | frequency | References |
---|---|---|
Tuareg from Tânout, Niger | 44.4% (8/18 subjects) | [49] |
Comorian Shirazi | 41% | [50] |
Tuareg from Gorom-Gorom, Burkina Faso | 16.6% (3/18) | [49] |
Tuareg from Gossi, Mali | 9.1% (1/9) | [49] |
Cape Verdeans |
15.9% (32/201) | [51] |
Maasai | 15.4% (4/26) | [11] |
Luo |
66% (6/9) | [11] |
Iraqw | 11.11% (1/9) | [11] |
Comoros | 23.46% (69/294) | [50] |
Merina people (also called Highlanders) | 44% (4/9) | [52] |
Antandroy | 69.6% (32/46) | [52] |
Antanosy | 48.9% (23/47) | [52] |
Antaisaka | 37.5% (3/8) | [52] |
E-M2 is found at low to moderate frequencies in North Africa, and Northeast Africa. Some of the lineages found in these areas are possibly due to the Bantu expansion or other migrations.[45][53] However, the discovery in 2011 of the E-M2 marker that predates E-M2 has led Trombetta et al. to suggest that E-M2 may have originated in East Africa.[5] In Eritrea and most of Ethiopia (excluding the Anuak), E-V38 is usually found in the form of E-M329, which is autochthonous, while E-M2 generally indicates Bantu migratory origins.[54][55][56]
Population group | frequency | References |
---|---|---|
Tuareg from Al Awaynat and Tahala, Libya | 46.5% (20/43)[a] | [57] |
Oran, Algeria | 8.6% (8/93) | [58] |
Berbers , southern and north-central Morocco |
9.5% (6/63) 5.8% (4/69) | [59][b][60] |
Moroccan Arabs | 6.8% (3/44) 1.9% (1/54) | [59][60] |
Saharawis |
3.5% (1/29) | [59] |
Egyptians | 1.4% (2/147), 0% (0/73), 8.33% (3/36) | [45][61][62] |
Tunisians | 1.4% (2/148) | [62] |
Sudanese (may include Hausa migrants) | 0.9% (4/445) | [63] |
Bantu minorities ) |
1.5% (3/201) | [53] |
Outside of Africa, E-M2 has been found at low frequencies. The clade has been found at low frequencies in West Asia. A few isolated occurrences of E-M2 have also been observed among populations in Southern Europe, such as Croatia, Malta, Spain and Portugal.[64][65][66][67]
Population group | frequency | References |
---|---|---|
Bahrain | 8.6% (46/562) | |
Saudi Arabians |
6.6% (11/157) | |
Omanis | 6.6% (8/121) | [45] |
Emiratis | 5.5% (9/164) | [70] |
Yemenis | 4.8% (3/62) | [70] |
Cypriots | 3.2% (2/62) | [67] |
Southern Iranians | 1.7% (2/117) | [71] |
Jordanians |
1.4% (2/139) | [72] |
Sri Lanka | 1.4% (9/638) | [73] |
Aeolian Islands, Italy | 1.2% (1/81) | [74] |
The Trans-Atlantic slave trade brought people to North America, Central America and South America including the Caribbean. Consequently, the haplogroup is often observed in the United States populations in men who self-identify as African Americans.[75] It has also been observed in a number of populations in Mexico, the Caribbean, Central America, and South America among people of African descent.
Population group | frequency | References |
---|---|---|
Americans | 7.7–7.9%[c] | [75] |
Cubans | 9.8% (13/132) | [76] |
Dominicans |
5.69% (2/26) | [77] |
Puerto Ricans | 19.23% (5/26) | [77] |
Nicaraguans | 5.5% (9/165) | [78] |
Several populations of Colombians | 6.18% (69/1116) | [79] |
Alagoas, Brazil | 4.45% (11/247) | [80] |
Bahia, Brazil | 19% (19/100) | [81] |
Bahamians | 58.63% (251/428) | [82] |
Subclades
E1b1a1

E1b1a1 is defined by markers DYS271/M2/SY81, M291, P1/PN1, P189, P293, V43, and V95. Whilst E1b1a reaches its highest frequency of 81% in Senegal, only 1 of the 139 Senegalese that were tested showed M191/P86.[48] In other words, as one moves to West Africa from western Central Africa, the less subclade E1b1a1f is found. Cruciani et al. (2002) states: "A possible explanation might be that haplotype 24 chromosomes [E-M2*] were already present across the Sudanese belt when the M191 mutation, which defines haplotype 22, arose in central western Africa. Only then would a later demic expansion have brought haplotype 22 chromosomes from central western to western Africa, giving rise to the opposite clinal distributions of haplotypes 22 and 24."[46]
E1b1a1a1
E1b1a1a1 is commonly defined by M180/P88. The basal subclade is quite regularly observed in M2+ samples.
E1b1a1a1a
E1b1a1a1a is defined by marker M58. 5% (2/37) of the town
E1b1a1a1b
E1b1a1a1b is defined by M116.2, a private marker. A single carrier was found in Mali.[12][d]
E1b1a1a1c
E1b1a1a1c is defined by private marker M149. This marker was found in a single South African.[12]
E1b1a1a1d
E1b1a1a1d is defined by a private marker M155. It is known from a single carrier in Mali.[12]
E1b1a1a1e
E1b1a1a1e is defined by markers M10, M66, M156 and M195. Wairak people in Tanzania tested 4.6% (2/43) positive for E-M10.[45] E-M10 was found in a single person of the Lissongo group in the Central African Republic and two members in a "Mixed" population from the Adamawa region.[12]
E1b1a1a1f
E1b1a1a1f is defined by L485. The basal node E-L485* appears to be somewhat uncommon but has not been sufficiently tested in large populations. The ancestral L485 SNP (along with several of its subclades) was very recently discovered. Some of these SNPs have little or no published population data and/or have yet to receive nomenclature recognition by the YCC.
- E1b1a1a1f1 is defined by marker L514. This SNP is currently without population study data outside of the 1000 Genomes Project.
- E1b1a1a1f1a (YCC E1b1a7) is defined by marker M191/P86. Filippo et al. (2011) studied a number of African populations that were E-M2 positive and found the basal E-M191/P86 (without E-P252/U174) in a population of Annang (38.3%), Ibibio (45.6%), Efik (45%), and Igbo (54.3%) living in Nigeria, West Africa.[85] E-M191/P86 appears in varying frequencies in Central and Southern Africa but almost all are also positive for P252/U174. Bantu-speaking South Africans (89/343) tested 25.9% positive and Khoe-San speaking South Africans tested 7.7% (14/183) positive for this SNP.[86] It also appears commonly in Africans living in the Americas. A population in Rio de Janeiro, Brazil tested 9.2% (12/130) positive.[83] 34.9% (29/83) of African American men tested positive for M191.[75]
- Veeramah et al. (2010) studies of the recombining portions of M191 positive Y chromosomes suggest that this lineage has "diffusely spread with multiple high frequency haplotypes implying a longer evolutionary period since this haplogroup arose".[85] The subclade E1b1a1a1f1a appears to express opposite clinal distributions to E1b1a1* in the West African Savanna region. Haplogroup E1b1a1a1f1a (E-M191) has a frequency of 23% in Cameroon (where it represents 42% of haplotypes carrying the DYS271 mutation or E-M2), 13% in Burkina Faso (16% of haplotypes carrying the M2/DYS271 mutation) and only 1% in Senegal.[48] Similarly, while E1b1a reaches its highest frequency of 81% in Senegal, only 1 of the 139 Senegalese that were tested showed M191/P86.[48] In other words, as one moves to West Africa from western Central Africa, the less subclade E1b1a1f is found. "A possible explanation might be that haplotype 24 chromosomes [E-M2*] were already present across the Sudanese belt when the M191 mutation, which defines haplotype 22, arose in central western Africa. Only then would a later demic expansion have brought haplotype 22 chromosomes from central western to western Africa, giving rise to the opposite clinal distributions of haplotypes 22 and 24."[46]
- E1b1a1a1f1a1 (YCC E1b1a7a) is defined by P252/U174. It appears to be the most common subclade of E-L485. It is believed to have originated near western Central Africa. It is rarely found in the most western portions of West Africa. Montano et al. (2011) found this subclade very prevalent in Nigeria and Gabon.[9] Filippo et al. (2011) estimated a tMRCA of ~4.2 kya from sample of Yoruba population positive for the SNP.[84]
- E1b1a1a1f1a1b (YCC E1b1a7a2) is defined by P115. This subclade has only been observed amongst Fang people of Central Africa.[9]
- E1b1a1a1f1a1c (YCC E1b1a7a3) is defined by P116. Montano et al. (2011) observed this SNP only in Gabon and a Bassa population from Cameroon.[9]
- E1b1a1a1f1a1d is defined by Z1704. This subclade has been observed across Africa. The 1000 Genomes Project Consortium found this SNP in Yoruba Nigerian, three Kenyan Luhyas and one African descent Puerto Rican.[87]
- E1b1a1a1f1b is defined by markers L515, L516, L517, and M263.2. This subclade was found by the researchers of Y-Chromosome Genome Comparison Project using data from the commercial bioinformatics company 23andMe.[88]
E1b1a1a1g
E1b1a1a1g (YCC E1b1a8) is defined by marker U175. The basal E-U175* is extremely rare. Montano et al. (2011) only found one out of 505 tested African subjects who was U175 positive but negative for U209.[9] Brucato et al. found similarly low frequencies of basal E-U175* in subjects in the Ivory Coast and Benin. Veeramah et al. (2010) found U175 in tested Annang (45.3%), Ibibio (37%), Efik (33.3%), and Igbo (25.3%) but did not test for U209.[85]
The supposed "Bantu haplotype" found in E-U175 carriers is "present at appreciable frequencies in other Niger–Congo languages speaking peoples as far west as Guinea-Bissau".[85] This is the modal haplotype of STR markers that is common in carriers of E-U175.[e]
E-U175 haplotype | DYS19 | DYS388 | DYS390 | DYS391 | DYS392 | DYS393 | |
15 | 12 | 21 | 10 | 11 | 13 | ||
E1b1a1a1g has several subclades.
- E1b1a1a1g1 (YCC E1b1a8a) is defined by U209. It is the most prominent subclade of U175. This subclade has very high frequencies of over fifty percentages in Cameroonian populations of Bassa and Bakaka, possibly indicating place of origin. However, E-U209 is widely found at lower frequencies in West and Central African countries surrounding Cameroon and Gabon.[9] Brucato et al. (2010) found the SNP in a populations of Ahizi (in Ivory Coast) 38.8% (19/49), Yacouba (Ivory Coast) 27.5% (11/40), and Beninese 6.5% (5/77) respectively.[89]
- E1b1a1a1g1a (YCC E1b1a8a1) is defined by U290. The Montano et al. (2011) study of U290 showed a lower frequency in Nigeria (11.7%) and western Central Africa than basal node U209. The highest population frequency rate in that study was 57.7% (15/26) in Ewondo in Cameroon.[9] 32.5% (27/83) of African American men tested by Sims et al. (2007) were positive for this SNP.[75]
- E1b1a1a1g1a2 is defined by Z1725. This marker has been observed by The 1000 Genomes Project Consortium in Yoruba Nigerians and Luhya Kenyans.[87]
- E1b1a1a1g1c (YCC E1b1a4) is defined by M154. A
- E1b1a1a1g1d is defined by V39. Trombetta et al. first published this SNP in 2011 but gave little population data about it.[5] It is only known to have been found in an African population.
E1b1a1a1h
E1b1a1a1h is defined by markers P268 and P269. It was first reported in a person from the
Phylogenetics
Phylogenetic history
Prior to 2002, there were in academic literature at least seven naming systems for the Y-Chromosome Phylogenetic tree. This led to considerable confusion. In 2002, the major research groups came together and formed the Y-Chromosome Consortium (YCC). They published a joint paper that created a single new tree that all agreed to use. Later, a group of citizen scientists with an interest in population genetics and genetic genealogy formed a working group to create an amateur tree aiming at being above all timely. The table below brings together all of these works at the point of the landmark 2002 YCC Tree. This allows a researcher reviewing older published literature to quickly move between nomenclatures.
YCC 2002/2008 (Shorthand) | (α) | (β) | (γ) | (δ) | (ε) | (ζ) | (η) | YCC 2002 (Longhand) | YCC 2005 (Longhand) | YCC 2008 (Longhand) | YCC 2010r (Longhand) | ISOGG 2006 | ISOGG 2007 | ISOGG 2008 | ISOGG 2009 | ISOGG 2010 | ISOGG 2011 | ISOGG 2012 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
E-P29 |
21 | III | 3A | 13 | Eu3 | H2 | B | E* | E | E | E | E | E | E | E | E | E | E |
E-M33 |
21 | III | 3A | 13 | Eu3 | H2 | B | E1* | E1 | E1a | E1a | E1 | E1 | E1a | E1a | E1a | E1a | E1a |
E-M44 | 21 | III | 3A | 13 | Eu3 | H2 | B | E1a | E1a | E1a1 | E1a1 | E1a | E1a | E1a1 | E1a1 | E1a1 | E1a1 | E1a1 |
E-M75 |
21 | III | 3A | 13 | Eu3 | H2 | B | E2a | E2 | E2 | E2 | E2 | E2 | E2 | E2 | E2 | E2 | E2 |
E-M54 | 21 | III | 3A | 13 | Eu3 | H2 | B | E2b | E2b | E2b | E2b1 | - | - | - | - | - | - | - |
E-P2 |
25 | III | 4 | 14 | Eu3 | H2 | B | E3* | E3 | E1b | E1b1 | E3 | E3 | E1b1 | E1b1 | E1b1 | E1b1 | E1b1 |
E-M2 |
8 | III | 5 | 15 | Eu2 | H2 | B | E3a* | E3a | E1b1 | E1b1a | E3a | E3a | E1b1a | E1b1a | E1b1a | E1b1a1 | E1b1a1 |
E-M58 | 8 | III | 5 | 15 | Eu2 | H2 | B | E3a1 | E3a1 | E1b1a1 | E1b1a1 | E3a1 | E3a1 | E1b1a1 | E1b1a1 | E1b1a1 | E1b1a1a1a | E1b1a1a1a |
E-M116.2 | 8 | III | 5 | 15 | Eu2 | H2 | B | E3a2 | E3a2 | E1b1a2 | E1b1a2 | E3a2 | E3a2 | E1b1a2 | E1b1a2 | E1ba12 | removed | removed |
E-M149 | 8 | III | 5 | 15 | Eu2 | H2 | B | E3a3 | E3a3 | E1b1a3 | E1b1a3 | E3a3 | E3a3 | E1b1a3 | E1b1a3 | E1b1a3 | E1b1a1a1c | E1b1a1a1c |
E-M154 | 8 | III | 5 | 15 | Eu2 | H2 | B | E3a4 | E3a4 | E1b1a4 | E1b1a4 | E3a4 | E3a4 | E1b1a4 | E1b1a4 | E1b1a4 | E1b1a1a1g1c | E1b1a1a1g1c |
E-M155 | 8 | III | 5 | 15 | Eu2 | H2 | B | E3a5 | E3a5 | E1b1a5 | E1b1a5 | E3a5 | E3a5 | E1b1a5 | E1b1a5 | E1b1a5 | E1b1a1a1d | E1b1a1a1d |
E-M10 | 8 | III | 5 | 15 | Eu2 | H2 | B | E3a6 | E3a6 | E1b1a6 | E1b1a6 | E3a6 | E3a6 | E1b1a6 | E1b1a6 | E1b1a6 | E1b1a1a1e | E1b1a1a1e |
E-M35 |
25 | III | 4 | 14 | Eu4 | H2 | B | E3b* | E3b | E1b1b1 | E1b1b1 | E3b1 | E3b1 | E1b1b1 | E1b1b1 | E1b1b1 | removed | removed |
E-M78 |
25 | III | 4 | 14 | Eu4 | H2 | B | E3b1* | E3b1 | E1b1b1a | E1b1b1a1 | E3b1a | E3b1a | E1b1b1a | E1b1b1a | E1b1b1a | E1b1b1a1 | E1b1b1a1 |
E-M148 | 25 | III | 4 | 14 | Eu4 | H2 | B | E3b1a | E3b1a | E1b1b1a3a | E1b1b1a1c1 | E3b1a3a | E3b1a3a | E1b1b1a3a | E1b1b1a3a | E1b1b1a3a | E1b1b1a1c1 | E1b1b1a1c1 |
E-M81 | 25 | III | 4 | 14 | Eu4 | H2 | B | E3b2* | E3b2 | E1b1b1b | E1b1b1b1 | E3b1b | E3b1b | E1b1b1b | E1b1b1b | E1b1b1b | E1b1b1b1 | E1b1b1b1a |
E-M107 | 25 | III | 4 | 14 | Eu4 | H2 | B | E3b2a | E3b2a | E1b1b1b1 | E1b1b1b1a | E3b1b1 | E3b1b1 | E1b1b1b1 | E1b1b1b1 | E1b1b1b1 | E1b1b1b1a | E1b1b1b1a1 |
E-M165 | 25 | III | 4 | 14 | Eu4 | H2 | B | E3b2b | E3b2b | E1b1b1b2 | E1b1b1b1b1 | E3b1b2 | E3b1b2 | E1b1b1b2a | E1b1b1b2a | E1b1b1b2a | E1b1b1b2a | E1b1b1b1a2a |
E-M123 |
25 | III | 4 | 14 | Eu4 | H2 | B | E3b3* | E3b3 | E1b1b1c | E1b1b1c | E3b1c | E3b1c | E1b1b1c | E1b1b1c | E1b1b1c | E1b1b1c | E1b1b1b2a |
E-M34 | 25 | III | 4 | 14 | Eu4 | H2 | B | E3b3a* | E3b3a | E1b1b1c1 | E1b1b1c1 | E3b1c1 | E3b1c1 | E1b1b1c1 | E1b1b1c1 | E1b1b1c1 | E1b1b1c1 | E1b1b1b2a1 |
E-M136 | 25 | III | 4 | 14 | Eu4 | H2 | B | E3ba1 | E3b3a1 | E1b1b1c1a | E1b1b1c1a1 | E3b1c1a | E3b1c1a | E1b1b1c1a1 | E1b1b1c1a1 | E1b1b1c1a1 | E1b1b1c1a1 | E1b1b1b2a1a1 |
Research publications
The following research teams per their publications were represented in the creation of the YCC tree.
Phylogenetic trees
This phylogenetic tree of haplogroup subclades is based on the Y-Chromosome Consortium (YCC) 2008 Tree,[92] the ISOGG Y-DNA Haplogroup E Tree,[7] and subsequent published research.
- E1b1a1 (DYS271/M2/SY81, M291, P1/PN1, P189, P293, V43, V95, Z1101, Z1107, Z1116, Z1120, Z1122, Z1123, Z1124, Z1125, Z1127, Z1130, Z1133)[f]
- E1b1a1a (L576)
- E1b1a1a1 (L86.1, L88.3, M180/P88, PAGES00066, P182, Z1111, Z1112)
- E1b1a1a1a (M58, PAGES00027)
- E1b1a1a1b (M116.2)
- E1b1a1a1c (M149)
- E1b1a1a1d (M155)
- E1b1a1a1e (M10, M66, M156, M195)
- E1b1a1a1f (L485)
- E1b1a1a1f1 (L514)
- E1b1a1a1f1a (M191/P86, P253/U247, U186, Z1712)
- E1b1a1a1f1a1 (P252/U174)
- E1b1a1a1f1a1a (P9.2)
- E1b1a1a1f1a1b (P115)
- E1b1a1a1f1a1c (P116)
- E1b1a1a1f1a1c1 (P113)
- E1b1a1a1f1a1d (Z1704)
- (L372)
- E1b1a1a1f1a1 (P252/U174)
- E1b1a1a1f1b (L515, L516, L517, M263.2)
- E1b1a1a1f1b1 (Z1893)
- (Z1894)
- E1b1a1a1f1b1 (Z1893)
- E1b1a1a1f1a (M191/P86, P253/U247, U186, Z1712)
- E1b1a1a1f1 (L514)
- E1b1a1a1g (U175)
- E1b1a1a1g1 (L220.3, L652, P277, P278.1, U209, M4254, M4230, CTS4921/M4243/V3224)
- E1b1a1a1g1a (U290)
- E1b1a1a1g1a1 (U181)
- E1b1a1a1g1a1a (L97)
- E1b1a1a1g1a2 (Z1725)
- E1b1a1a1g1a1 (U181)
- E1b1a1a1g1b (P59)
- E1b1a1a1g1c (M154)
- E1b1a1a1g1d (V39)
- E1b1a1a1g1a (U290)
- E1b1a1a1g1 (L220.3, L652, P277, P278.1, U209, M4254, M4230, CTS4921/M4243/V3224)
- E1b1a1a1h (P268, P269)
- E1b1a1a1 (L86.1, L88.3, M180/P88, PAGES00066, P182, Z1111, Z1112)
- E1b1a1a (L576)
- E1b1a1 (DYS271/M2/SY81, M291, P1/PN1, P189, P293, V43, V95, Z1101, Z1107, Z1116, Z1120, Z1122, Z1123, Z1124, Z1125, Z1127, Z1130, Z1133)[f]
See also
Genetics
- African admixture in Europe
- Genetic genealogy
- Haplogroup D
- Haplogroup DE
- Haplogroup
- Haplotype
- Human Y-chromosome DNA haplogroup
- Molecular phylogenetics
- Paragroup
- Subclade
- Y-chromosome haplogroups in populations of the world
- Y-DNA haplogroups by ethnic group
- Y-DNA haplogroups in populations of Sub-Saharan Africa
Y-DNA E subclades
- Haplogroup E-L485
- Haplogroup E-M123
- Haplogroup E-M180
- Haplogroup E-M215
- Haplogroup E-M33
- Haplogroup E-M521
- Haplogroup E-M75
- Haplogroup E-M96
- Haplogroup E-P147
- Haplogroup E-P177
- Haplogroup E-P2
- Haplogroup E-V12
- Haplogroup E-V13
- Haplogroup E-V22
- Haplogroup E-V38
- Haplogroup E-M2
- Haplogroup E-V65
- Haplogroup E-V68
- Haplogroup E-Z820
- Haplogroup E-Z827
Y-DNA backbone tree
Notes
- ^ All were positive for U175.
- ^ The publication refers to E-V38 as H22.
- ^ E-M2 is approximately 7.7–7.9% of total US male population.
- ^ The publication transposes M116.2 with M116.1 in Table 1.
- ^ The YCAII STR marker value of 19–19 is also usually indicative of U175.
- ^ DYS271/M2/SY81, P1/PN1, P189, P293, and M291 appear to form E1b1a1*. L576 forms a subclade immediately after the previously mentioned SNPs. L576 gave rise to a deeper subclade of M180/P88, P182, L88.3, L86, and PAGES0006. From this subclade, all the major subclades (i.e. E-U175 and E-L485) of E1b1a evolved. The exact position of V43 and V95 within these three subclades and E1b1a1a1b (M116.2), E1b1a1a1c (M149), and E1b1a1a1d (M155) remains uncertain.
References
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Sources for conversion tables
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- Jobling, Mark A.; Tyler-Smith, Chris (2000), "New uses for new haplotypes", Trends in Genetics, 16 (8): 356–62, PMID 10904265
- Kaladjieva, Luba; Calafell, Francesc; Jobling, Mark A; Angelicheva, Dora; et al. (February 2001). "Patterns of inter- and intra-group genetic diversity in the Vlax Roma as revealed by Y chromosome and mitochondrial DNA lineages". European Journal of Human Genetics. 9 (2): 97–104. PMID 11313742.
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External links
- Haplogroup E1b1a FTDNA Project
- Distribution of E1b1a/E3a in Africa
- Spread of Haplogroup E3a, from National Geographic