Henry Hallett Dale
GBE FRS | |
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Born | Henry Hallett Dale 9 June 1875 |
Died | 23 July 1968 | (aged 93)
Education | Tollington School The Leys School |
Alma mater | |
Known for | |
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Scientific career | |
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Website | www |
Sir Henry Hallett Dale
Early life and education
Henry Hallett Dale was born in Islington, London, to Charles James Dale, a pottery manufacturer from Staffordshire, and his wife, Frances Anne Hallett, daughter of a furniture manufacturer, from South Devon.[1][9] Henry was the third of seven children, one of whom (his younger brother, Benjamin Dale) became an accomplished composer and warden of the Royal Academy of Music. Henry was educated at the local Tollington Park College and then The Leys School Cambridge (one of the school's houses is named after him) and in 1894 entered Trinity College, Cambridge,[10] working under the physiologist John Langley. For a few months in 1903 he also studied under Paul Ehrlich in Frankfurt, Germany. Also in 1903, Dale assisted Ernest Starling and William Bayliss in the vivisection of a dog, by removing the dog's pancreas and then killing the dog with a knife, which ultimately led to the events of the Brown Dog affair. Dale received his Doctor of Medicine degree from Cambridge in 1909.[11][3]
Career and research
While working at the University College London, he met and became friends with Otto Loewi. Dale became the director of the Department of Biochemistry and Pharmacology at the National Institute for Medical Research in London in 1914. He became a Fullerian Professor of Chemistry at the Royal Institution in 1942.[12] During World War II he served on the scientific advisory panel to the Cabinet.
Although Dale and his colleagues first identified acetylcholine in 1914 as a possible neurotransmitter, Loewi showed its importance in the nervous system. The two men shared the 1936 Nobel Prize for Medicine.
During the 1940s Dale was embroiled in the scientific debate over the nature of signaling at the
Dale also originated the scheme used to differentiate
Between 1938 and 1960 Dale served as
Awards and honours
Dale was elected a
Personal life
In 1904, Dale had married his first cousin Ellen Harriett Hallett and had a son and two daughters. One of their daughters, Alison Sarah Dale, married
Dales's residency at the house is marked by a Greater London Council blue plaque erected in 1981 on the garden wall of the house.[20]
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Dale as a child
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Dale in 1904
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Dale in 1918
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Dale with wife
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Son of Henry Hallett Dale
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The Nobel Prize diploma of Dale, displayed in the Royal Society, London.
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Dale-Schuster blood pump
See also
References
- ^ S2CID 7383038.
- ISBN 9780851159195. Retrieved 20 March 2016.
- ^ EThOS uk.bl.ethos.294137.
- PMID 4896522.
- PMID 4890938.
- ISBN 978-0-684-10114-9.
- ^ Abigail O'Sullivan: Henry Dale's Nobel Prize winning 'discovery'. Minerva, 2001; 38: 409–424. [ISBN missing]
- ^ Sabbatini, R.M.E.: Neurons and synapses. The history of its discovery. IV. Chemical transmission. Brain & Mind, 2004.
- ^ "Dale, Henry Hallett (DL894HH)". A Cambridge Alumni Database. University of Cambridge.
- ^ Henry Hallett Dale on Nobelprize.org , accessed 1 May 2020
- ^ "Fullerian Professorships".
- ^ Anon (2015). "Biography of Henry Hallett Dale (1875–1968)". rigb.org. London: Royal Institution. Archived from the original on 8 March 2016.
- ^ "Henry Hallett Dale". American Academy of Arts & Sciences. Retrieved 12 May 2023.
- ^ "APS Member History". search.amphilsoc.org. Retrieved 12 May 2023.
- ^ "Henry Dale". www.nasonline.org. Retrieved 12 May 2023.
- ^ Anon (2016). "Sir Henry Dale Fellowships". wellcome.ac.uk. London: Wellcome Trust. Archived from the original on 22 June 2016.
- ^ "Medals | Society for Endocrinology".
- ISBN 978-1-4050-4925-2.
- ^ "DALE, Sir Henry (1875–1968)". English Heritage. Retrieved 4 July 2020.
External links
- Henry Hallett Dale on Nobelprize.org including the Nobel Lecture, 12 December 1936 Some Recent Extensions of the Chemical Transmission of the Effects of Nerve Impulses