Hexamidine

Source: Wikipedia, the free encyclopedia.
Hexamidine
Skeletal formula of hexamidine
Ball-and-stick model
Names
Preferred IUPAC name
4,4′-[Hexane-1,6-diylbis(oxy)]di(benzene-1-carboximidamide)
Other names
4-[6-(4-carbamimidoylphenoxy)hexoxy]benzamidine
Identifiers
3D model (
JSmol
)
ChEBI
ChEMBL
ChemSpider
DrugBank
UNII
  • InChI=1S/C20H26N4O2/c21-19(22)15-5-9-17(10-6-15)25-13-3-1-2-4-14-26-18-11-7-16(8-12-18)20(23)24/h5-12H,1-4,13-14H2,(H3,21,22)(H3,23,24) checkY
    Key: OQLKNTOKMBVBKV-UHFFFAOYSA-N checkY
  • InChI=1/C20H26N4O2/c21-19(22)15-5-9-17(10-6-15)25-13-3-1-2-4-14-26-18-11-7-16(8-12-18)20(23)24/h5-12H,1-4,13-14H2,(H3,21,22)(H3,23,24)
    Key: OQLKNTOKMBVBKV-UHFFFAOYAW
  • O(c1ccc(cc1)C(=[N@H])N)CCCCCCOc2ccc(C(=[N@H])N)cc2
Properties
C20H26N4O2
Molar mass 354.446
Pharmacology
D08AC04 (WHO) R01AX07 (WHO) R02AA18 (WHO) S01AX08 (WHO) S03AA05 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Hexamidine is an

lipid membranes of pathogens. Hexamidine and its shorter congener, propamidine, are used as antiseptics and preservatives in pharmaceuticals and cosmetics. They are particularly used for the topical treatment of acanthamoebiasis (Acanthamoeba keratitis).[2]

References

  1. S2CID 2059780
    .
  2. S2CID 3385063


drug article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Hexamidine&oldid=1192053320"