Human adenovirus 41

Classification

Human adenovirus 41 belongs to the Adenoviridae family, and along with human adenovirus 40, is a member of species human mastadenovirus F.^[4][5]

Pathology

It can particularly target the

In an investigation of 5 children with an inflammation of the liver (hepatitis) of unknown cause at Birmingham, Alabama in October 2021, all turned out to have human adenovirus 41.^[6] In August 2022, 9 children in a U.S. case series of hepatitis of unknown cause^[7] and 27 of 30 children in a U.K. case series with hepatitis of unknown cause who underwent molecular testing^[8] tested positive for human adenovirus type 41 in a sample. It was unclear whether human adenovirus 41 was the cause, however.^{[citation needed]}

Diagnosis

It cannot be detected using traditional cell culture isolation,^[3] but can be detected by using molecular based assays and enzyme immunoassay.^[2]

Epidemiology

Globally it is a significant cause of

It was first identified in 1983.[11]

References