Human body

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Human anatomy
)

Female (left) and male (right) adult human bodies photographed in ventral (above) and dorsal (below) perspectives. Naturally-occurring pubic, body, and facial hair have been deliberately removed to show anatomy.

The human body is the entire structure of a

organ systems. They ensure homeostasis and the viability
of the human body.

It consists of

feet
.

The study of the human body includes

varies anatomically in known ways. Physiology focuses on the systems and organs of the human body and their functions. Many systems and mechanisms interact in order to maintain homeostasis, with safe levels of substances such as sugar and oxygen
in the blood.

The body is studied by health professionals, physiologists, anatomists, and artists to assist them in their work.

Composition

Elements of the human body by mass.
Trace elements
are less than 1% combined (and each less than 0.1%).
Element Symbol Percent mass Percent atoms
Oxygen O 65.0 24.0
Carbon C 18.5 12.0
Hydrogen H 9.5 62.0
Nitrogen N 3.2 1.1
Calcium Ca 1.5 0.22
Phosphorus P 1.0 0.22
Potassium K 0.4 0.03
Sulfur S 0.3 0.038
Sodium Na 0.2 0.037
Chlorine Cl 0.2 0.024
Magnesium Mg 0.1 0.015
Trace elements < 0.1 < 0.3

The human body is composed of elements including hydrogen, oxygen, carbon, calcium and phosphorus. These elements reside in trillions of cells and non-cellular components of the body.

The adult male body is about 60%

interstitial fluid, and about 23 litres (5.1 imp gal; 6.1 US gal) of fluid inside cells.[1] The content, acidity and composition of the water inside and outside cells is carefully maintained. The main electrolytes in body water outside cells are sodium and chloride, whereas within cells it is potassium and other phosphates.[2]

Cells

The body contains trillions of cells, the fundamental unit of life. At maturity, there are roughly 30 trillion cells, and 38 trillion bacteria in the body,[3][4] an estimate arrived at by totaling the cell numbers of all the organs of the body and cell types. The skin of the body is also host to billions of commensal organisms as well as immune cells.[5] Not all parts of the body are made from cells. Cells sit in an extracellular matrix that consists of proteins such as collagen, surrounded by extracellular fluids.

Genome

Cells in the body function because of

red blood cells
lose their nucleus as they mature.

Tissues

The body consists of many different types of

muscle tissue.[9]

Cells that lie on surfaces exposed to the outside world or gastrointestinal tract (

cilia in the lungs, to column-like cells that line the stomach. Endothelial cells are cells that line internal cavities including blood vessels and glands. Lining cells regulate what can and cannot pass through them, protect internal structures, and function as sensory surfaces.[9]

Organs

cavities within the body. These cavities include the abdomen (which contains the stomach, for example) and pleura
, which contains the lungs.

Heart

The heart is an organ located in the thoracic cavity between the lungs and slightly to the left. It is surrounded by the pericardium, which holds it in place in the mediastinum and serves to protect it from blunt trauma, infection and help lubricate the movement of the heart via pericardial fluid.[11] The heart works by pumping blood around the body allowing oxygen, nutrients, waste, hormones and white blood cells to be transported.

Diagram of the human heart

The heart is composed of two atria and two ventricles. The primary purpose of the atria is to allow uninterrupted venous blood flow to the heart during ventricular systole. This allows enough blood to get into the ventricles during atrial systole. Consequently, the atria allows a cardiac output roughly 75% greater than would be possible without them.[12] The purpose of the ventricles is to pump blood to the lungs through the right ventricle and to the rest of the body through the left ventricle.[13]

The heart has an

pump blood into the ventricles. It then travels to the atrioventricular node, which makes the signal slow down slightly allowing the ventricles to fill with blood before pumping it out and starting the cycle over again.[14]

Coronary artery disease is the leading cause of death worldwide, making up 16% of all deaths.[15] It is caused by the buildup of plaque in the coronary arteries supplying the heart, eventually the arteries may become so narrow that not enough blood is able to reach the myocardium,[16] a condition known as myocardial infarction or heart attack, this can cause heart failure or cardiac arrest and eventually death.[17] Risk factors for coronary artery disease include obesity, smoking, high cholesterol, high blood pressure, lack of exercise and diabetes.[18] Cancer can affect the heart, though it is exceedingly rare and has usually metastasized from another part of the body such as the lungs or breasts. This is because the heart cells quickly stop dividing and all growth occurs through size increase rather than cell division.[19]

Gallbladder

The gallbladder is a hollow pear-shaped organ located

inferior middle part of the right lobe of the liver. It is variable in shape and size. It stores bile before it is released into the small intestine via the common bile duct to help with digestion of fats. It receives bile from the liver via the cystic duct, which connects to the common hepatic duct to form the common bile duct.[20]

The gallbladder gets its blood supply from the cystic artery, which in most people, emerges from the right hepatic artery.[20]

Gallstones is a common disease in which one or more stones form in the gallbladder or biliary tract. Most people are asymptomatic but if a stone blocks the biliary tract, it causes a gallbladder attack, symptoms may include sudden pain in the upper right abdomen and or center of the abdomen. Nausea and vomiting may also occur. Typical treatment is removal of the gallbladder through a procedure called a cholecystectomy.[21][22] Having gallstones is a risk factor for gallbladder cancer, which although quite uncommon, is rapidly fatal if not diagnosed early.[23]

Systems

  • Circulatory system

The

hormones) from one part of the body to another. Paths of blood circulation within the human body can be divided into two circuits: the pulmonary circuit, which pumps blood to the lungs to receive oxygen and leave carbon dioxide, and the systemic circuit, which carries blood from the heart off to the rest of the body. The blood consists of fluid that carries cells in the circulation, including some that move from tissue to blood vessels and back, as well as the spleen and bone marrow.[24][25][26]

  • Digestive system
Digestive system

The

gastrointestinal tract, small and large intestines, and rectum), as well as the liver, pancreas, gallbladder, and salivary glands. It converts food into small, nutritional, non-toxic molecules for distribution and absorption into the body. These molecules take the form of proteins (which are broken down into amino acids), fats, vitamins and minerals (the last of which are mainly ionic rather than molecular). After being swallowed, food moves through the gastrointestinal tract by means of peristalsis: the systematic expansion and contraction of muscles to push food from one area to the next.[27][28]

Digestion begins in the mouth, which chews food into smaller pieces for easier digestion. Then it is swallowed, and moves through the esophagus to the stomach. In the stomach, food is mixed with gastric acids to allow the extraction of nutrients. What is left is called chyme; this then moves into the small intestine, which absorbs the nutrients and water from the chyme. What remains passes on to the large intestine, where it is dried to form feces; these are then stored in the rectum until they are expelled through the anus.[28]

  • Endocrine system

The

parathyroids, and gonads, but nearly all organs and tissues produce specific endocrine hormones as well. The endocrine hormones serve as signals from one body system to another regarding an enormous array of conditions, resulting in variety of changes of function.[29]

  • Immune system

The

toll-like receptors, among many others.[30]

Skin
  • Integumentary system

The integumentary system consists of the covering of the body (the skin), including hair and nails as well as other functionally important structures such as the sweat glands and sebaceous glands. The skin provides containment, structure, and protection for other organs, and serves as a major sensory interface with the outside world.[31][32]

  • Lymphatic system

The lymphatic system extracts, transports and metabolizes lymph, the fluid found in between cells. The lymphatic system is similar to the circulatory system in terms of both its structure and its most basic function, to carry a body fluid.[33]

  • Musculoskeletal system

The

joints and cartilage) and attached muscles. It gives the body basic structure and the ability for movement. In addition to their structural role, the larger bones in the body contain bone marrow, the site of production of blood cells. Also, all bones are major storage sites for calcium and phosphate. This system can be split up into the muscular system and the skeletal system.[34]

  • Nervous system
Nervous system

The

smell. The eyes, ears, tongue, and nose gather information about the body's environment.[35]

From a structural perspective, the nervous system is typically subdivided into two component parts: the central nervous system (CNS), composed of the brain and the spinal cord; and the peripheral nervous system (PNS), composed of the nerves and ganglia outside the brain and spinal cord. The CNS is mostly responsible for organizing motion, processing sensory information, thought, memory, cognition and other such functions.[36] It remains a matter of some debate whether the CNS directly gives rise to consciousness.[citation needed] The peripheral nervous system (PNS) is mostly responsible for gathering information with sensory neurons and directing body movements with motor neurons.[36]

From a functional perspective, the nervous system is again typically divided into two component parts: the somatic nervous system (SNS) and the autonomic nervous system (ANS). The SNS is involved in voluntary functions like speaking and sensory processes. The ANS is involved in involuntary processes, such as digestion and regulating blood pressure.[37]

The nervous system is subject to many different diseases. In

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a motor neuron disease which gradually reduces movement in patients. There are also many other diseases of the nervous system.[36]

  • Reproductive system
ovaries
, right)

The purpose of the

genitalia
.

Internal gross anatomy of the female reproductive system

Female puberty generally occurs between the ages of 9 and 13 and is characterized by ovulation and menstruation; the growth of secondary sex characteristics, such as growth of pubic and underarm hair, breast, uterine and vaginal growth, widening hips and increased height and weight, also occur during puberty.[39] Male puberty sees the further development of the penis and testicles.[40]

The female inner sex organs are the two ovaries, their

vaginal opening).[42][39]

The male external genitalia include the penis and

.

Diseases that affect the reproductive system include polycystic ovary syndrome,[43] a number of disorders of the testicles including testicular torsion,[44][45] and a number of sexually transmitted infections including syphilis, HIV, chlamydia, HPV and genital warts. [46][47] Cancer can affect most parts of the reproductive system including the penis, testicles, prostate, ovaries, cervix, vagina, fallopian, uterus and vulva.[48]

  • Respiratory system

The

bloodstream.[49][50]

For the respiratory system to function properly, there need to be as few impediments as possible to the movement of air within the lungs. Inflammation of the lungs and excess mucus are common sources of breathing difficulties.[50] In asthma, the respiratory system is persistently inflamed, causing wheezing and/or shortness of breath. Pneumonia occurs through infection of the alveoli, and may be caused by tuberculosis. Emphysema, commonly a result of smoking, is caused by damage to connections between the alveoli.[51]

  • Urinary system
Female urinary system

The

bladder, and urethra. It removes waste materials from the blood through urine, which carries a variety of waste molecules and excess ions
and water out of the body.

First, the

bladder
.

The smooth muscle lining the ureter walls continuously tighten and relax through a process called peristalsis to force urine away from the kidneys and down into the bladder. Small amounts of urine are released into the bladder every 10–15 seconds.

The bladder is a hollow balloon shaped organ located in the pelvis. It stores urine until the brain signals it to relax the urinary sphincter and release the urine into the urethra starting urination.[54] A normal bladder can hold up to 16 ounces (half a liter) for 3–5 hours comfortably.

Numerous diseases affect the urinary system including kidney stones, which are formed when materials in the urine concentrate enough to form a solid mass, urinary tract infections, which are infections of the urinary tract and can cause pain when urinating, frequent urination and even death if left untreated. Renal failure occurs when the kidneys fail to adequately filter waste from the blood and can lead to death if not treated with dialysis or kidney transplantation.[55] Cancer can affect the bladder, kidneys, urethra and ureters, with the latter two being far more rare.[56]

Anatomy

Cavities of human body

Human anatomy is the study of the shape and form of the human body. The human body has four limbs (two arms and two legs), a head and a neck, which connect to the torso. The body's shape is determined by a strong skeleton made of bone and cartilage, surrounded by fat (adipose tissue), muscle, connective tissue, organs, and other structures. The spine at the back of the skeleton contains the flexible vertebral column, which surrounds the spinal cord, which is a collection of nerve fibres connecting the brain to the rest of the body. Nerves connect the spinal cord and brain to the rest of the body. All major bones, muscles, and nerves in the body are named, with the exception of anatomical variations such as sesamoid bones and accessory muscles.

Blood vessels carry blood throughout the body, which moves because of the beating of the

capillaries, then small veins and the process begins again. Blood carries oxygen, waste products, and hormones from one place in the body to another. Blood is filtered at the kidneys and liver
.

The body consists of a number of

.

Height, weight,

Physiology

Human

bioelectrical, and biochemical functions of humans in good health, from organs to the cells of which they are composed. The human body consists of many interacting systems of organs. These interact to maintain homeostasis, keeping the body in a stable state with safe levels of substances such as sugar and oxygen in the blood.[58]

Each system contributes to homeostasis, of itself, other systems, and the entire body. Some combined systems are referred to by joint names. For example, the nervous system and the endocrine system operate together as the

nerve impulses and neurotransmitters. At the same time, the endocrine system releases hormones, such as to help regulate blood pressure and volume. Together, these systems regulate the internal environment of the body, maintaining blood flow, posture, energy supply, temperature, and acid balance (pH).[58]

Development

Baby being carried

Development of the human body is the process of growth to maturity. The process begins with fertilisation, where an egg released from the

aging
.

Society and culture

Professional study

Anatomical study by Leonardo da Vinci

Health professionals learn about the human body from illustrations, models, and demonstrations. Medical and dental students in addition gain practical experience, for example by dissection of cadavers. Human anatomy, physiology, and biochemistry are basic medical sciences, generally taught to medical students in their first year at medical school.[59][60][61]

Depiction

Figure drawing by Lovis Corinth (before 1925)

In Western societies, the contexts for depictions of the human body include information, art and pornography. Information includes both science and education, such as anatomical drawings. Any ambiguous image not easily fitting into one of these categories may be misinterpreted, leading to disputes.[62] The most contentious disputes are between fine art and erotic images, which define the legal distinction of which images are permitted or prohibited.

History of anatomy

Two facing pages of text with woodcuts of naked male and female figures, in the Epitome by Andreas Vesalius, 1543

In

ultrasound imaging to study the body in unprecedented detail.[68]

History of physiology

The study of human physiology began with

George Bartholomew extended their studies to comparative physiology and ecophysiology.[71] Most recently, evolutionary physiology has become a distinct subdiscipline.[72]

See also

Human body lists

References

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Books

External links