IL17RB
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Interleukin-17 receptor B is a protein that in humans is encoded by the IL17RB gene.[5][6][7]
The protein encoded by this gene is a
NF-κB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.[7]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000056736 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015966 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 10749887.
- S2CID 27521628.
- ^ a b "Entrez Gene: IL17RB interleukin 17 receptor B".
Further reading
- Schwandner R, Yamaguchi K, Cao Z (2000). "Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction". J. Exp. Med. 191 (7): 1233–40. PMID 10748240.
- Lee J, Ho WH, Maruoka M, et al. (2001). "IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1". J. Biol. Chem. 276 (2): 1660–4. PMID 11058597.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. PMID 12975309.
- Hillman RT, Green RE, Brenner SE (2005). "An unappreciated role for RNA surveillance". Genome Biol. 5 (2): R8. PMID 14759258.
- Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. PMID 15340161.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMID 15489334.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. PMID 16344560.
- Symmans WF (2006). "Genomic testing for sensitivity of breast cancer to hormonal therapy". Clin. Cancer Res. 12 (7 Pt 1): 1954–5. PMID 16609001.
- Goetz MP, Suman VJ, Ingle JN, et al. (2006). "A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen". Clin. Cancer Res. 12 (7 Pt 1): 2080–7. S2CID 9930864.
- Ma XJ, PMID 17008703.
External links
- IL17RB+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.