IRAK2

Source: Wikipedia, the free encyclopedia.
IRAK2
Available structures
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_001570

NM_001113553
NM_172161

RefSeq (protein)

NP_001561

NP_001107025
NP_751893

Location (UCSC)Chr 3: 10.16 – 10.24 MbChr 6: 113.62 – 113.67 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene.[5][6]

Function

IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.[6]

Interactions

IRAK2 has been shown to

Myd88.[5][7][8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134070 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060477 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^
    PMID 9374458
    .
  6. ^ a b "Entrez Gene: IRAK2 interleukin-1 receptor-associated kinase 2".
  7. ^
    PMID 10383454
    .
  8. .

Further reading

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