Impetigo herpetiformis

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Impetigo herpetiformis
Other namesPustular psoriasis of pregnancy
SpecialtyDermatology, obstetrics Edit this on Wikidata

Impetigo herpetiformis is a form of severe pustular psoriasis occurring in pregnancy[1][2] which may occur during any trimester.[3][4]

Signs and symptoms

The typical lesions are centrifugally extending

pustules; they can also develop erosion, crust, and impetiginization. These lesions are mainly seen in flexural regions. Patients may experience vegetative lesions resembling Pemphigus vegetans, though they are uncommon.[5] It is possible to see mucosal lesions in the tongue, mouth, and even esophagus in addition to nail involvement.[6]

In impetigo herpetiformis, hypoparathyroidism and hypocalcemia may be encountered.[7] Systematic symptoms such as malaise, hypovolemic shock, vomiting, chills, fever, diarrhea, and seizures may also be seen.[8]

Causes

The cause of impetigo herpetiformis is not yet clear.[8] Some evidence suggests that genetic factors may play a role in the development of impetigo herpetiformis, such as the number of familial cases.[9]

Diagnosis

The diagnosis of impetigo herpetiformis is supported by clinical and laboratory findings, and

acanthosis, and papillomatosis with focal parakeratosis.[10] Spongiform pustules of Kogoj are intraepidermal multilocular microabscesses that are formed by neutrophil collections.[11]

Laboratory findings include iron deficiency anemia, hypoalbuminemia, hypocalcemia, elevated erythrocyte sedimentation rate, and leukocytosis.[12]

Treatment

Pustular psoriasis is still primarily treated with systemic

cyclosporine may be a useful medication.[14] In impetigo herpetiformis, the use of antibiotics appears to be beneficial, despite the fact that they cannot completely eradicate the illness.[15][16]

See also

References

  1. ISBN 0-7216-2921-0
    .
  2. PMID 17263216
    .
  3. ^ "DermIS — Impetigo Herpetiformis (Information on the diagnosis)". Archived from the original on 2018-08-08. Retrieved 2009-11-29.
  4. ISBN 978-1-4160-2999-1
    .
  5. PMID 29849579
    .
  6. PMID 20072676
    .
  7. S2CID 46004532
    .
  8. ^
    PMID 10926744
    .
  9. S2CID 42807497
    .
  10. PMID 24346915
    .
  11. ISSN 0100-7203
    .
  12. S2CID 21334983
    .
  13. S2CID 42999570
    .
  14. PMID 23626548
    .
  15. S2CID 37248288
    .
  16. S2CID 253808218
    .

Further reading

External links
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