Polyphagia

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Increased appetite
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Polyphagia
Other namesHyperphagia
SpecialtyEndocrinology, Psychiatry

Polyphagia or hyperphagia is an abnormally strong,

diabetes mellitus.[2]

Etymology and pronunciation

The word polyphagia (

, from the Greek words πολύς (polys), "very much" or "many", and φᾰ́γω (phago), "eating" or "devouring".

Underlying conditions and possible causes

Polyphagia is one of the most common symptoms of diabetes mellitus. It is associated with hyperthyroidism and endocrine diseases, e.g., Graves' disease, and it has also been noted in Prader–Willi syndrome and other genetic conditions caused by chromosomal anomalies. It is only one of several diagnostic criteria for bulimia and is not by itself classified as an eating disorder. As a symptom of Kleine–Levin syndrome, it is sometimes termed megaphagia.[3]

Knocking out vagal nerve receptors has been shown to cause hyperphagia.[4]

Changes in hormones associated with the female menstrual cycle can lead to extreme hunger right before the period. Spikes in estrogen and progesterone and decreased serotonin can lead to cravings for carbohydrates and fats.[5]

Polyphagia is found in the following conditions:[6]

Polyphagia in diabetes

Diabetes mellitus causes a disruption in the body's ability to transfer glucose from food into energy. Polyphagia in

T1D. In T1D, it probably results from cellular starvation and the depletion of cellular stores of carbohydrates, fats, and proteins.[5][7]

See also

References

  1. ^ "Polyphagia". Human Phenotype Ontology. Archived from the original on 2 March 2022. Retrieved 6 October 2022.
  2. ^ Diabetes.co.uk
  3. PMID 14023898
    .
  4. .
  5. ^ a b "Polyphagia". Cleveland Clinic. 2023. Retrieved 3 June 2023.
  6. ^ "Polyphagia (Concept Id: C0020505) - MedGen - NCBI".
  7. ISBN 978-1-4698-8829-3.{{cite book}}: CS1 maint: date and year (link
    )

External links