Polyphagia
Polyphagia | |
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Other names | Hyperphagia |
Specialty | Endocrinology, Psychiatry |
Polyphagia or hyperphagia is an abnormally strong,
Etymology and pronunciation
The word polyphagia (, from the Greek words πολύς (polys), "very much" or "many", and φᾰ́γω (phago), "eating" or "devouring".
Underlying conditions and possible causes
Polyphagia is one of the most common symptoms of diabetes mellitus. It is associated with hyperthyroidism and endocrine diseases, e.g., Graves' disease, and it has also been noted in Prader–Willi syndrome and other genetic conditions caused by chromosomal anomalies. It is only one of several diagnostic criteria for bulimia and is not by itself classified as an eating disorder. As a symptom of Kleine–Levin syndrome, it is sometimes termed megaphagia.[3]
Knocking out vagal nerve receptors has been shown to cause hyperphagia.[4]
Changes in hormones associated with the female menstrual cycle can lead to extreme hunger right before the period. Spikes in estrogen and progesterone and decreased serotonin can lead to cravings for carbohydrates and fats.[5]
Polyphagia is found in the following conditions:[6]
- Chromosome 22q13 duplication syndrome
- Chromosome 2p25.3 deletion (MYT1L Syndrome)
- Chromosome Xq26.3 duplication syndrome
- Congenital generalized lipodystrophy type 1
- Congenital generalized lipodystrophy type 2
- Diabetes mellitus type 1
- Familial renal glucosuria
- Frontotemporal dementia
- Frontotemporal dementia, ubiquitin-positive
- Graves' disease
- Hypotonia-cystinuria syndrome
- Kleine–Levin syndrome
- Leptin deficiency or dysfunction
- Leptin receptor deficiency
- Luscan-lumish syndrome
- Macrosomia adiposa congenita
- Mental retardation, autosomal dominant 1
- Obesity, hyperphagia, and developmental delay (OBHD)
- Pick's disease
- Prader–Willi syndrome
- Proopiomelanocortin deficiency
- Schaaf-yang syndrome
Polyphagia in diabetes
Diabetes mellitus causes a disruption in the body's ability to transfer glucose from food into energy. Polyphagia in
See also
- Anorexia
- Binge eating
- Charles Domery
- Compulsive overeating
- Counterregulatory eating
- Eating disorder
- Effects of cannabis
- Erysichthon of Thessaly
- Hedonic hunger
- Tarrare
References
- ^ "Polyphagia". Human Phenotype Ontology. Archived from the original on 2 March 2022. Retrieved 6 October 2022.
- ^ Diabetes.co.uk
- PMID 14023898.
- PMID 25161883.
- ^ a b "Polyphagia". Cleveland Clinic. 2023. Retrieved 3 June 2023.
- ^ "Polyphagia (Concept Id: C0020505) - MedGen - NCBI".
- ISBN 978-1-4698-8829-3.)
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