Internal elastic lamina
The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels. It separates tunica intima from tunica media.
Histology
It is readily visualized with
smooth muscle cells in their tunica media, the internal elastic lamina is approximately the same thickness as the other elastic laminae that are normally present.[2]
There is small amount of subendothelial connective tissue between basement membrane of endothelial cells and internal elastic lamina.[3]
Reduplication of internal elastic lamina can be seen in elderly individuals due to
aging process.[4]
Associated pathologic conditions
- Damage in van Gieson stain aids in diagnosis of giant cell arteritis. It stains muscle tissue in yellow, connective tissue in red and elastic structures (like internal elastic lamina) in black color.[4]
- In chronic allograft nephropathy, disruption or reduplication of internal elastic lamina can be observed, which causes narrowing of the lumen and downstream ischemia.[5]
- In fungal rhinosinusitis, the organism has predilection for internal elastic lamina during phase of spread.[6]
References
- ^ a b "Study and Revise Histology Online with Meyer's Histology".
- ^ "Cardiovascular System".
- ^ Histology Image Review. McGraw-Hill. 2007. pp. (Fig. 9–25).
- ^ ISBN 9780727917799.
- ^ Clinical Nephrology Dialysis and Transplantation. Dustri-Verlag Feistle. 2004. pp. 21, 22 (of section III-5).
- ISBN 1-55009-045-3.