International AIDS Vaccine Initiative
New York, NY | |
Website | https://www.iavi.org |
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The International AIDS Vaccine Initiative (IAVI) is a global
History
In 1994, the
The International AIDS Vaccine Initiative was founded in 1996 by
In February 2023, Muhammad Ali Pate was appointed chairman of the Vaccine Alliance (Gavi), which works to provide vaccines in low-income countries.[4]
Activities
IAVI's scientific team, drawn largely from private industry, researches and develops AIDS vaccine candidates and engages in clinical trials and research through partnerships with more than 100 academic, biotechnology, pharmaceutical and governmental institutions.[1]
In September 2009, a global group of researchers led by IAVI published a study in the journal Science identifying PG9 and PG16, two highly powerful broadly neutralizing antibodies against a wide variety of HIV variants.[5] The site on the virus to which PG9 and PG16 attach revealed a vulnerability on HIV.[6] PG9 and PG16 were the first new broadly neutralizing antibodies against HIV discovered in more than a decade and are the result of a global effort launched in 2006.[7]
Partnerships
To address major obstacles in AIDS vaccine development, IAVI partners with HIV researchers from around the world. Its Neutralizing Antibody Center is a network dedicated to discovering and understanding broadly neutralizing
IAVI is a founding member of the Global HIV Vaccine Enterprise, an alliance of independent organizations working towards an AIDS vaccine.[2] It also partners with civil society organizations and other entities to advocate jointly for the development of AIDS vaccines, and is a member of the Global Health Technologies Coalition, an alliance of more than 30 non-profit groups that aims to increase awareness of the urgent need for technologies that save lives in developing countries.[8]
Donors
IAVI's work is funded by donors including: the Bill & Melinda Gates Foundation, the Coalition for Epidemic Preparedness Innovations, the Ministry of Foreign Affairs of Denmark, Irish Aid, the Ministry of Finance of Japan in partnership with The World Bank, the Ministry of Foreign Affairs of the Netherlands, the United Kingdom Department for International Development, and the United States Agency for International Development (USAID).
See also
- Seth Berkley
- Clinical trial
- Advance market commitments
References
- ^ a b Berkley, Seth. (2006). Ending an epidemic: the International AIDS Vaccine Initiative pioneers a public-private partnership. Innovations, Vol. 1, No. 1. 52–66.
- ^ a b c Holtzman, J. (2009). International Aids Vaccine Initiative. TechImpact @ Yale, 3(1), 1-2.
- ISBN 978-1-351-15542-7.
- ^ Rédaction Africanews avec AFp (14 February 2023). "Muhammad Ali Pate, un Nigérian pour diriger l'Alliance du vaccin". Africanews.
- ^ Cohen, Jon (2009). Potent Antibodies Spark Vaccine Hopes. Science, Vol. 325. no. 5945, p. 1195
- ^ "Two New Antibodies Found to Cripple HIV," Theraclone Sciences news release. Sept. 3, 2009.
- ^ Phogat, Sanjay. "Antibody Discoveries Latest Advance in AIDS Vaccine Research Renaissance," Global Health Magazine blog. July 17, 2010.
- ^ Global Health Technologies Coalition Archived 2010-12-28 at the Wayback Machine website. Retrieved Aug. 3, 2010