Interneuron
Interneuron | |
---|---|
Details | |
Location | Nervous system |
Identifiers | |
MeSH | D007395 |
NeuroLex ID | birnlex_2534 |
TH | H2.00.06.1.00058 |
FMA | 67313 |
Anatomical terms of neuroanatomy |
Interneurons (also called internuncial neurons, relay neurons, association neurons, connector neurons, intermediate neurons or local circuit neurons) are
]Interneurons can be further broken down into two groups: local interneurons and relay interneurons.[4][need quotation to verify] Local interneurons have short axons and form circuits with nearby neurons to analyze small pieces of information.[5] Relay interneurons have long axons and connect circuits of neurons in one region of the brain with those in other regions.[5] However, interneurons are generally considered to operate mainly within local brain areas.[6] The interaction between interneurons allow the brain to perform complex functions such as learning, and decision-making.
Structure
Approximately 20–30% of the neurons in the
In 2008, a nomenclature for the features of GABAergic cortical interneurons was proposed, called Petilla terminology.[10]
Spinal cord
- Ia inhibitory interneuron: Found in lamina VII. Responsible for inhibiting antagonist motor neuron. 1a spindle afferents activate 1a inhibitory neuron.
- Ib inhibitory interneuron: Found in lamina V, VI, VII. Afferent or Golgi tendon organ activates it.
Cortex
- Parvalbumin-expressing interneurons
- CCK-expressing interneurons
- VIP-expressing interneurons
- SOM-expressing interneurons[11]
Cerebellum
- Molecular layer (basket cells, stellate cells)
- Golgi cells
- Granule cells
- Lugaro cells
- Unipolar brush cells
Striatum
- Parvalbumin-expressing interneurons[12]
- Cholinergic interneurons[13][14]
- Tyrosine hydroxylase-expressing interneurons[15]
- Calretinin-expressing interneurons[16]
- Nitric oxide synthase-expressing interneurons[16]
Function
Interneurons in the CNS are primarily
In addition to these general functions, interneurons in the insect CNS play a number of specific roles in different parts of the nervous system, and also are either excitatory or inhibitory. For example, in the olfactory system, interneurons are responsible for integrating information from odorant receptors and sending signals to the mushroom bodies, which are involved in learning and memory.[17][18] In the visual system, interneurons are responsible for processing motion information and sending signals to the optic lobes, which are involved in visual navigation.[19][20]
Interneurons are also important for coordinating complex behaviors, such as flight and locomotion. For example, interneurons in the thoracic ganglia are responsible for coordinating the activity of the leg muscles during walking[21] and flying.[22]
Interneurons main function is to provide a neural circuit, conducting flow of signals or information between a sensory neuron and or motor neuron.[23]
See also
References
- ^ Pearson, K. G. and Wolf, H. Connections of hindwing tegulae with flight neurones in the locust, Locusta migratoria. J. Exp. Biol. 135: 381-409, 1988
- ^ "Types of neurons - Queensland Brain Institute - University of Queensland". 9 November 2017.
- PMID 11102670.
- ISBN 978-0-205-23939-9.
- ^ ISBN 978-0-8385-7701-1.
- PMID 24429630.
- S2CID 382334.
- ^ S2CID 3377296.
- S2CID 44969376.
- PMID 18568015.
- PMID 28254942.
- S2CID 16088859.
- PMID 12436423.
- PMID 22158514.
- PMID 20484642.
- ^ PMID 21228905.
- PMID 29884811.
- PMID 35797998.
- PMID 23880926.
- PMID 35839763.
- PMID 32822613.
- S2CID 10530883.
- ^ "Types of Neurons". University of Queensland. Queensland Brain Institute. 9 November 2017. Retrieved 26 April 2023.