Interstitium
Interstitium | |
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Anatomical terminology |
The interstitium is a
Structure
The non-fluid parts of the interstitium are predominantly
The interstitium in the submucosae of visceral organs, the dermis, superficial fascia, and perivascular adventitia are fluid-filled spaces supported by a collagen bundle lattice. The fluid spaces communicate with draining lymph nodes though they do not have lining cells or structures of lymphatic channels.[6]
Functions
The interstitial fluid is a reservoir and transportation system for nutrients and solutes distributing among organs, cells, and
The total fluid volume of the interstitium during health is about 20% of body weight, but this space is dynamic and may change in volume and composition during immune responses and in conditions such as
Disease
In people with lung diseases, heart disease, cancer, kidney disease, immune disorders, and periodontal disease, the interstitial fluid and lymph system are sites where disease mechanisms may develop.[2][4][5][7]
See also
References
- ISBN 0683072021.
- ^ PMID 22811424.
- ^ a b Scallan J; Huxley VH; Korthuis RJ (2010). The Interstitium. In: Capillary Fluid Exchange: Regulation, Functions, and Pathology. San Rafael, CA: Morgan & Claypool Life Sciences. Archived from the original on 2021-02-08. Retrieved 2018-03-29.
- ^ PMID 22108723.
- ^ PMID 25813241.
- PMID 29588511.
- PMID 24503053.