Cellular compartment

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(Redirected from
Intracellular compartment
)
Basic cellular compartments

Cellular compartments in

membrane-bound organelles
. The formation of cellular compartments is called compartmentalization.

Both

microtubules
can also be counted as compartments.

It was thought that compartmentalization is not found in prokaryotic cells.,[1] but the discovery of carboxysomes and many other metabolosomes revealed that prokaryotic cells are capable of making compartmentalized structures, albeit these are in most cases not surrounded by a lipid bilayer, but of pure proteinaceous built.[2][3][4]

Types

In general, there are 4 main cellular compartments, they are:

  1. The nuclear compartment comprising the nucleus
  2. The intercisternal space which comprises the space between the membranes of the endoplasmic reticulum (which is continuous with the nuclear envelope)
  3. Organelles (the mitochondrion in all eukaryotes and the plastid in phototrophic eukaryotes)
  4. The cytosol

Function

Compartments have three main roles. One is to establish physical boundaries for biological processes that enables the cell to carry out different metabolic activities at the same time. This may include keeping certain biomolecules within a region, or keeping other molecules outside. Within the membrane-bound compartments, different

NADH
to NAD+. With these cases, the compartmentalization is physical.

Another is to generate a specific micro-environment to spatially or temporally regulate a biological process. As an example, a yeast vacuole is normally acidified by proton transporters on the membrane.

A third role is to establish specific locations or cellular addresses for which processes should occur. For example, a

Golgi body
is also near the rough ER for packaging and redistributing. Likewise, intracellular compartmentalization allows specific sites of related eukaryotic cell functions isolated from other processes and therefore efficient.

Establishment

Often, cellular compartments are defined by membrane enclosure. These membranes provide physical barriers to biomolecules. Transport across these barriers is often controlled in order to maintain the optimal concentration of biomolecules within and outside of the compartment.

Emergence of the eukaryotic nucleus

The eukaryotic cell is thought to have arisen when an ancestral archaeal cell internalized an aerobic bacterium (the proto-mitochondrion). Mans et al.[5] proposed that the evolutionary development of the eukaryotic cell nucleus was triggered by this archaeo-bacterial symbiosis. The nuclear envelope (membrane), a defining characteristic of the eukaryotic cell, was suggested to have arisen as an adaptation for segregating the original archaeal host DNA genome away from the proto-mitochondria, the main source of damaging reactive oxygen species.[6]

References

  1. ISBN 978-0-8053-6844-4
    .
  2. PMID 30113887
    .
  3. PMID 23240612
    .
  4. PMID 24440431
    .
  5. ^ Mans BJ, Anantharaman V, Aravind L, Koonin EV. Comparative genomics, evolution and origins of the nuclear envelope and nuclear pore complex. Cell Cycle. 2004 Dec;3(12):1612-37. doi: 10.4161/cc.3.12.1345. Epub 2004 Dec 20. PMID 15611647
  6. ^ Bernstein H, Bernstein C. Sexual communication in archaea, the precursor to meiosis. pp. 103-117 in Biocommunication of Archaea (Guenther Witzany, ed.) 2017. Springer International Publishing

External links

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