Isolated organ perfusion technique
Isolated organ perfusion technique is employed to precipitate an organ's perfusion and circulation that are independent/isolated from the body's systemic circulation for various purposes such as organ-localized chemotherapy, organ-targeted delivery of drug, gene or anything else, organ transplantation, and organ injury recovery. The technique has been widely studied in animal and human for decades.[1][2][3][4][5][6][7] Before the implementation, the perfusion system will be selected and the process can be similar to organ bath.[8] Isolated organ perfusion technique, nevertheless, is averagely conducted in vivo without leaving the organ alone as a whole out of the body.[9]
See also
- ECMO
References
- PMID 27112253.
- PMID 13726167. Retrieved 2019-06-30.
- ^ "Isolated Organ Perfusion Studies - Physiology". Harvard Apparatus. Archived from the original on 2019-05-13. Retrieved 2019-06-30.
- PMID 5578880.
- S2CID 7397409.
- PMID 26445796.
- S2CID 29637802.
- ^ "Tissue bath" (PDF). Archived (PDF) from the original on 2017-06-18. Retrieved 2019-06-30.
- ISBN 978-1-4612-7325-7.
Technological advances in artificial perfusion allow effective isolated perfusion of a wide variety of organs and tissues, including, but not limited to, brain, heart, lung, heart-lung, liver, kidney, spleen, pancreas, thymus, gastrointestinal tract, urinary tract, reproductive tract, skeletal muscle, nerves, and blood vessels.