JWH-007

Source: Wikipedia, the free encyclopedia.
Not to be confused with JHW-007, an atypical dopamine reuptake inhibitor.
JWH-007
Legal status
Legal status
Identifiers
  • 1-Pentyl-2-methyl-3-(1-naphthoyl)indole
JSmol)
  • c14ccccc4cccc1C(=O)c3c2ccccc2n(c3C)CCCCC
  • InChI=1S/C25H25NO/c1-3-4-9-17-26-18(2)24(22-14-7-8-16-23(22)26)25(27)21-15-10-12-19-11-5-6-13-20(19)21/h5-8,10-16H,3-4,9,17H2,1-2H3
  • Key:IBBNKINXTRKICJ-UHFFFAOYSA-N
  (verify)

JWH-007 is an

desmethyl derivative of JWH-007, JWH-018, has slightly higher binding affinity for CB1, with an optimum binding of 9.00 nM at CB1 and 2.94 nM at CB2, and JWH-007 displayed optimum binding of 9.50 nM at CB1 and 2.94 nM at CB2.[6]

Legal status

In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as JWH-007 are

Schedule I Controlled Substances.[7]

JWH-007 was banned in Sweden on 1 October 2010 after being identified as an ingredient in "herbal"

synthetic cannabis products.[8][9]

JWH-007 has been illegal in Poland since August 2010[10]

As of October 2015 JWH-007 is a controlled substance in China.[11]

See also

References

  1. doi:10.1016/s0960-894x(01)80155-4
    .
  2. PMID 8666005
    .
  3. PMID 1335057
    .
  4. PMID 15582455
    .
  5. PMID 15974991
    .
  6. PMID 10940540
    .
  7. ^ 21 U.S.C. § 812: Schedules of controlled substances
  8. ^ Swedish Code of Statutes Regulation (2010:1086).
  9. ^ "Swedish Code of Statutes Regulation (2010:1086). (pdf)" (PDF). Archived from the original (PDF) on 2011-07-28. Retrieved 2011-01-10.
  10. ^ "Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 )". ISAP. Retrieved 12 June 2011.
  11. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
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