JWH-057

JWH-057

Identifiers
IUPAC name (6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-Dibenzo[b,d]pyran
JSmol)	Interactive image
SMILES CCCCCCC(C)(C)C1=CC2=C(C=C1)[C@@H]3CC(=CC[C@H]3C(O2)(C)C)C
InChI InChI=1S/C25H38O/c1-7-8-9-10-15-24(3,4)19-12-13-20-21-16-18(2)11-14-22(21)25(5,6)26-23(20)17-19/h11-13,17,21-22H,7-10,14-16H2,1-6H3/t21-,22+/m0/s1 Key:JEEFMLVJZKFOFV-FCHUYYIVSA-N

JWH-057, also known as deoxy-Δ8-THC-DMH, is a selective cannabinoid ligand, with a binding affinity of K_i = 2.9 ± 1.6 nM for the CB₂ subtype, and K_i = 23 ± 7 nM for CB₁.^[1]

See also

• JWH-015
• JWH-018
• JWH-019
• JWH-073

References