JWH-176

Source: Wikipedia, the free encyclopedia.
(Redirected from
JWH-171
)

JWH-176
Legal status
Legal status
Identifiers
  • 1-([(1E)-3-Pentylinden-1-ylidine]methyl)naphthalene
JSmol)
  • CCCCCC1=C\C(=C/c2cccc3ccccc32)c2ccccc21
  • InChI=1S/C25H24/c1-2-3-4-11-21-18-22(25-16-8-7-15-24(21)25)17-20-13-9-12-19-10-5-6-14-23(19)20/h5-10,12-18H,2-4,11H2,1H3/b22-17+
  • Key:FPESBQVTVSBBSE-OQKWZONESA-N
  (verify)

JWH-176 is an

hydrogen bonding capacity at all, relying merely on Van der Waals and possibly hydrophobic interactions to bind to the receptor.[2] It was discovered by, and named after, John W. Huffman
.

Stereochemistry

JWH-176 is the (E)-stereoisomer of 1-([3-pentylinden-1-ylidine]methyl)naphthalene, whereas JWH-171 is the mixture of the (E)- and (Z)-isomers.[3]

JWH-171

Legal status

In the United States, CB1 receptor agonists of the 1-(1-naphthylmethylene)indene class such as JWH-176 and JWH-171 are

Schedule I Controlled Substances.[4]

As of 23 December 2009, any compound structurally derived from 1–(1–naphthylmethyl)indene by substitution at the 3–position of the indene ring by an alkyl group is a Class B drug in the United Kingdom.[5]

See also

References

  1. PMID 15974991
    .
  2. ISBN 3-540-22565-X
    .
  3. ISBN 978-1-60805-346-9
    .
  4. ^ 21 U.S.C. § 812: Schedules of controlled substances
  5. ^ "The Misuse of Drugs Act 1971 (Amendment) Order 2009", legislation.gov.uk, The National Archives, SI 2009/3209
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