Juno Therapeutics
CEO & President)Steve Harr, M.D. ( CFO )Hyam Levitsky, M.D. ( CSO )Mark Gilbert, M.D. ( Bristol-Myers Squibb | |
| Website | www |
|---|---|
Juno Therapeutics Inc was an American biopharmaceutical company founded in 2013 through a collaboration of the
On January 22, 2018, Juno Therapeutics was acquired by biotechnology company Celgene for $9 billion.[2]
In November 2019,
History
In December 2014 the company signed an agreement with Opus Bio, Inc for a
In April 2015 the company entered into a collaboration with
In January 2016 Juno announced it had acquired AbVitro, allowing it to use next-generation single cell sequencing platforms to complement its ability to create T cells engineered to target a broad array of cancer targets.[11] Later in July of the same year, the company announced it would acquire RedoxTherapies for $10 million.[12] This acquisition provides Juno with an exclusive license to vipadenant, a small molecule adenosine A2a (A2a) receptor antagonist that has the potential to disrupt important immunosuppressive pathways in the tumor microenvironment in certain cancers. In August the company announced it would license rights from Memorial Sloan Kettering Cancer Center and Eureka Therapeutics for a novel, fully human binding domain targeting B-cell maturation antigen.[13]
In January 2018, Celgene announced it would acquire Juno for $9 billion.[14]
| Juno Therapeutics |
| |||||||||
Drug approval
- chimeric antigen receptor (CAR) T-cell immunotherapy with a defined composition of purified CD8+ and CD4+ CAR T cells for the treatment of adult patients with relapsed or refractory (R/R) large B-cell lymphoma after at least two prior therapies.[15] On February 5, 2021, the U.S. Food and Drug Administration approved Breyanzi (lisocabtagene maraleucel), a cell-based gene therapy to treat adult patients with certain types of large B-cell lymphoma who have not responded to, or who have relapsed after, at least two other types of systemic treatment.[16]
See also
References
- ^ a b "News Release". Juno Therapeutics.
- ISSN 0099-9660. Retrieved 2018-01-22.
- ^ Bristol-Myers Squibb Completes Acquisition of Celgene, Creating a Leading Biopharma Company, PM BMS, November 20, 2019; retrieved May 20, 2020
- ^ "News Release". Juno Therapeutics.
- ^ "MedImmune, Juno Team Up to Study Cancer Immunotherapy Combo". GEN. 23 April 2015.
- ^ "Juno Therapeutics Buys Stage Cell Therapeutics for Up-to-$233M". GEN. 12 May 2015.
- Genetic Engineering & Biotechnology News. Retrieved 2016-02-11.
- ^ "Juno Therapeutics Acquires X-Body for $44M+". GEN. 2 June 2015.
- ^ "Celgene Launches $1B Immunotherapy Collaboration with Juno". GEN. 30 June 2015.
- ^ Doni Bloomfield (29 June 2015). "Juno Rises as Celgene Pays $1 Billion to Buy Cancer Stake". Bloomberg.com.
- ^ "Juno's AbVitro Acquisition Adds Sequencing to Repertoire - GEN". GEN. Retrieved 24 August 2017.
- ^ "Juno Buys RedoxTherapies for $10M+ - GEN". GEN. 15 July 2016. Retrieved 24 August 2017.
- ^ "Juno Licenses BCMA from MSK, Eureka Therapeutics - GEN". GEN. 5 August 2016. Retrieved 24 August 2017.
- ^ Erman, Ben Hirschler, Sudip Kar-Gupta, Michael (January 22, 2018). "Biotech M&A takes off as Sanofi and Celgene spend $20 billion". Reuters – via www.reuters.com.
{{cite news}}: CS1 maint: multiple names: authors list (link) - ^ U.S. Food and Drug Administration (FDA) Accepts for Priority Review Bristol-Myers Squibb’s Biologics License Application (BLA) for Lisocabtagene Maraleucel (liso-cel) for Adult Patients with Relapsed or Refractory Large B-Cell Lymphoma, PM BMS February 13, 2020; retrieved May 20, 2020
- ^ Commissioner, Office of the (2021-02-05). "FDA Approves New Treatment For Adults With Relapsed Or Refractory Large-B-Cell Lymphoma". FDA. Retrieved 2021-02-07.
