Kennel cough

upper respiratory infection affecting dogs.^[1] There are multiple causative agents, the most common being the bacterium Bordetella bronchiseptica (found in 78.7% of cases in Southern Germany), followed by canine parainfluenza virus (CPIV; 37.7% of cases), and to a lesser extent canine coronavirus (9.8% of cases).^[2] It is highly contagious;^[3] however, adult dogs may display immunity to reinfection even under constant exposure.^[4] Kennel cough is so named because the infection can spread quickly among dogs in the close quarters of a kennel or animal shelter

spread through airborne droplets produced by sneezing and coughing. These agents also spread through contact with contaminated surfaces. Symptoms begin after a several day incubation period post-exposure,^[3] and in most cases will clear up on their own. However, in young puppies or immunocompromised animals, mixed or secondary infections can progress to lower respiratory infections such as pneumonia.^[5]

trachea or after excitement or exercise. The presence of a fever varies from case to case.^{[citation needed}

canine mastadenovirus A (formerly canine adenovirus-1). This form occurs most regularly in autumn, and can be distinguished by symptoms such as a retching cough and vomiting. The second form has a more complex combination of causative organisms, including CDV and CAV. It typically occurs in dogs that have not been vaccinated and it is not seasonal. Symptoms are more severe than the first form, and may include rhinitis, conjunctivitis, and fever, in addition to a hacking cough.^[6]

parainfluenza or Canine respiratory coronavirus are only spread for roughly one week following recovery;^[5] however, respiratory infections involving B. bronchiseptica can be transmissible for several weeks longer.^[4] While there was early evidence to suggest that B. bronchiseptica could be shed for many months post-infection,^[4] a more recent report places detectable nasal and pharyngeal levels of B. bronchiseptica in 45.6% of all clinically healthy dogs.^[2] This has potentially expanded the vector from currently or recently infected dogs to half the dog population as carriers. To put the relative levels of shedding bacteria into perspective, a study analyzing the shedding kinetics of B. bronchiseptica presents the highest levels of bacterial shedding one week post-exposure, with an order of magnitude decrease in shedding observed every week.^[7] This projection places negligible levels of shedding to be expected six weeks post-exposure (or approximately five weeks post-onset of symptoms). Dogs which had been administered intranasal vaccine four weeks prior to virulent B. bronchiseptica challenge displayed little to no bacterial shedding within three weeks of exposure to the virulent strain.^[7]

NSAIDs are often given to reduce fever and upper respiratory inflammation. Prevention is by vaccinating for canine adenovirus, distemper, parainfluenza, and Bordetella. In kennels, the best prevention is to keep all the cages disinfected. In some cases, such as "doggie daycares" or nontraditional playcare-type boarding environments, it is usually not a cleaning or disinfecting issue, but rather an airborne issue, as the dogs are in contact with each other's saliva and breath. Although most kennels require proof of vaccination, the vaccination is not a fail-safe preventative. Just like human influenza, even after receiving the vaccination, a dog can still contract mutated strains or less severe cases.^{[citation needed}

adenovirus in addition to B. bronchiseptica and canine parainfluenza virus antigens. Studies have thus far not been able to determine which formula of vaccination is the most efficient. Adverse effects of vaccinations are mild, but the most common effect observed up to 30 days after administration is nasal discharge.^[8] Vaccinations are not always effective. In one study it was found that 43.3% of all dogs in the study population with respiratory disease had in fact been vaccinated.^[2]

radiographic examinations. Findings will be mild in animals affected only by kennel cough, while those with complications may have evidence of segmental atelectasis (collapsed lung) and other severe side effects.^[10]