Kenneth H. Wolfe

Source: Wikipedia, the free encyclopedia.

Ken Wolfe

EMBO Member (2010)[1]
Scientific career
FieldsComparative genomics
Yeast genetics
Bioinformatics[2]
InstitutionsUniversity College Dublin
Trinity College Dublin
Indiana University Bloomington[3]
ThesisRates of nucleotide substitution in higher plants and mammals (1990)
Doctoral advisorPaul M. Sharp[4][5][6]
Other academic advisorsJeffrey D. Palmer[7]
Doctoral students
Websitewolfe.ucd.ie

Kenneth Henry Wolfe

MRIA[11][12] is an Irish geneticist and professor of genomic evolution at University College Dublin (UCD), Ireland.[13][11][14]

Education

Wolfe was educated at

PhD in 1990[6] for research investigating synonymous substitution in vascular plants and mammals supervised by Paul M. Sharp.[4][5][6][15]

Research and career

Wolfe's research focuses on

genome duplication about 100 million years ago,[18] an event that is now known to be the result of hybridization between two divergent species.[12] This finding reshaped our understanding both of yeast biology, and of mechanisms of genome evolution in eukaryotes.[12] His subsequent discoveries of similar ancient genome duplications (paleopolyploidy)[19] during human evolution, and in almost all families of flowering plants, led to the realisation that whole-genome duplication is widespread.[12] His group also studies the origin and evolution of mating systems in yeasts, and the process of mating-type switching in which one cell type can change into another by moving or replacing a section of chromosome.[12]

Wolfe was a postdoctoral researcher with Jeffrey D. Palmer[7] at Indiana University Bloomington before returning to Ireland in 1992 to establish his research group in the genetics department of Trinity College Dublin,[20][3] where he remained for over 20 years. In 2013, he moved to University College Dublin's UCD School of Medicine and Conway Institute.[21] As of 2017 his most highly cited peer reviewed papers[2][14][16] have been published in leading scientific journals including Nature,[18][22] PNAS,[23] The Plant Cell,[19][24] Genome Research[25] and Nature Reviews Genetics.[7]

Former doctoral students from the Wolfe lab include Mario A. Fares,[4] Aoife McLysaght,[4][8][9] Estelle Proux-Wéra[4] and Cathal Seoighe.[5][10]

Awards and honours

Wolfe was elected a

Fellow of the Royal Society (FRS) in 2017,[12] a member of the Royal Irish Academy (MRIA) in 2000[11] and a member of the European Molecular Biology Organization (EMBO) in 2010.[1] In 2011 he served as president of the Society for Molecular Biology and Evolution (smbe.org).[26]

References

  1. ^ a b Anon (2010). "EMBO member: Kenneth H. Wolfe". people.embo.org. Heidelberg: European Molecular Biology Organization. Archived from the original on 31 January 2017.
  2. ^ a b c Kenneth H. Wolfe publications indexed by Google Scholar Edit this at Wikidata
  3. ^
  4. ^ a b c d e f g h Anon (2017). "Kenneth H. Wolfe academic genealogy". academictree.org. Archived from the original on 11 July 2017.
  5. ^ a b c d Kenneth H. Wolfe at the Mathematics Genealogy Project
  6. ^ .
  7. ^ . (subscription required)
  8. ^ (PDF) on 6 November 2017.
  9. ^ a b Wolfe, Ken (2017). "Wolfe lab alumni". wolfe.ucd.ie. Archived from the original on 11 July 2017.
  10. ^
    ProQuest 301607379
    .
  11. ^ a b c Anon (2000). "Kenneth H. Wolfe FTCD". ria.ie. Dublin: Royal Irish Academy. Archived from the original on 11 December 2017. Retrieved 14 July 2017.
  12. ^ a b c d e f g Anon (2017). "Professor Kenneth Wolfe FRS". royalsociety.org. London: Royal Society. Archived from the original on 5 May 2017. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --"Royal Society Terms, conditions and policies". Archived from the original on 11 November 2016. Retrieved 9 March 2016.{{cite web}}: CS1 maint: bot: original URL status unknown (link)

  13. YouTube
    , University College Dublin
  14. ^ a b Kenneth H. Wolfe publications from Europe PubMed Central
  15. PMID 3138659
    .
  16. ^ a b Kenneth H. Wolfe publications indexed by the Scopus bibliographic database. (subscription required)
  17. PMID 27806045. Open access icon
  18. ^ . (subscription required)
  19. ^ .
  20. ^ "Trinity College Dublin Genetics Department". www.tcd.ie.
  21. ^ "Ken Wolfe Profile". people.ucd.ie.
  22. PMID 11237011
    .
  23. .
  24. .
  25. .
  26. ^ Anon (2017). "SMBE Council members". smbe.org. Archived from the original on 10 October 2017. Retrieved 22 September 2017.