Kveim test
| Kveim test | |
|---|---|
| Synonyms | Kveim-Siltzbach test |
| MeSH | D007731 |
The Kveim test, Nickerson-Kveim or Kveim-Siltzbach test is a
false negative result. The test is not commonly performed, and in the UK no substrate has been available since 1996. There is a concern that certain infections, such as bovine spongiform encephalopathy, could be transferred through a Kveim test.[1]
It is named for the Norwegian
pathologist Morten Ansgar Kveim, who first reported the test in 1941 using lymph node tissue from sarcoidosis patients.[2][3] It was popularised by the American physician Louis Siltzbach, who introduced a modified form using spleen tissue in 1954.[4] Kveim's work was a refinement of earlier studies performed by Nickerson, who in 1935 first reported on skin reactions in sarcoid.[5]
A Kveim test may be used to distinguish sarcoidosis from conditions with otherwise indistinguishable symptoms such as berylliosis.[6]
References
- ^ "Kveim test". GPnotebook.
- ^ Kveim MA (1941). "En ny og spesifikk kutan-reaksjon ved Boecks sarcoid. En foreløpig meddelelse". Nordisk Medicin (in Norwegian). 9: 169–172.
- Who Named It?
- PMID 13158367.
- S2CID 86958986.
- PMID 20386622.
External links
- Kveim+test at the U.S. National Library of Medicine Medical Subject Headings (MeSH)