Laboratory animal allergy
Laboratory animal allergy (LAA) is an
laboratory animal technicians and scientists.[1][2] It manifests as an allergic response to animal urine, specifically the major urinary proteins (Mups) of rodents, and can lead to the development of asthma.[3] A study of 5641 workers in Japan who were exposed to laboratory animals found 23.1% had one or more allergic symptoms; globally the prevalence among at risk workers is estimated between 11 and 30% [4] According to the National Institutes of Health, prevention of animal allergy depends on the control of allergens in the work environment. This involves a combination of measures to eliminate or control allergen exposure, including engineering controls, administrative controls, and personal protective equipment.[5]
The protein product of the mouse Mup17 gene,antibodies to Rat n 1.[8]
