Leland H. Hartwell
Leland H. Hartwell | |
|---|---|
| Born | October 30, 1939 Los Angeles, California, U.S. |
| Alma mater | Biodesign Institute Amrita Vishwa Vidyapeetham |
Leland Harrison (Lee) Hartwell (born October 30, 1939) is former president and director of the
Working in yeast, Hartwell identified the fundamental role of checkpoints in cell cycle control, and CDC genes such as CDC28, which controls the start of the cycle—the progression through G1.[2]
Education
Hartwell attended
Awards and honors
In addition to the
In 1998 he received the
Research
His earliest publications focused on the isolation of temperature sensitive yeast mutants disabled in basic biological processes, including DNA, RNA and protein synthesis.[10] This led to the identification of the CDC (Cell Division Cycle) genes, which function in promoting the progression through cell division, most notably CDC28, which encodes the yeast Cdk kinase. Other significant discoveries include introduction of the concept of cell cycle "checkpoints", which delay cell division when cellular insults are generated and also the identification and characterization of the mating signal transduction pathway.
Other positions
Hartwell is the Chairman of the Scientific Advisory Board at the
Lee Hartwell Award
This award is given to scientists whose research in yeast has made the most impact in the broader areas of biology. Recipients of the award also give a lecture at the biennial Yeast Genetics Meeting.[15]
- 2016 – Susan Gasser, Friedrich Miescher Institute for Biomedical Research
- 2014 – George Church, Harvard Medical School
- 2012 – Stan Fields, University of Washington, Seattle
- 2010 – Randy Schekman, University of California, Berkeley
- 2008 – Mitsuhiro Yanagida, Kyoto University
- 2006 – Kim Nasmyth, Oxford University
- 2004 – Susan Lindquist, Whitehead Institute
- 2002 – Leland Hartwell, Fred Hutchinson Cancer Research Center
References
- ^ "Leland H. Hartwell - A Superstar of Science".
- ^ a b "The Nobel Prize in Physiology or Medicine 2001, Illustrated Lecture".
- ^ Paulson, Tom (October 8, 2001). "It's Now Dr. Hartwell, Nobel Laureate". Seattle Post-Intelligencer.
- PMID 5271168.
- ^ Tore Frängsmyr., ed. (2002). Les Prix Nobel. The Nobel Prizes 2001. Nobel Foundation: Stockholm.
- ^ Leland H. Hartwell on Nobelprize.org , accessed 11 October 2020
- ^ "Lee Hartwell's profile, Community of Science". Archived from the original on April 27, 2006.
- ^ "The Official Site of Louisa Gross Horwitz Prize". June 14, 2018.
- ^ Luke Timmerman for Xconomy. September 20, 2010 Lee Hartwell, at 70, Tackles Personalized Medicine, Education in Latest Career Phase
- PMID 5337848.
- ^ Pacific Health Summit, About the Summit, 2011 Archived March 4, 2016, at the Wayback Machine
- ^ Hartwell to join ASU faculty ASU News
- ^ Arizona State University and Virginia G. Piper Charitable Trust tap Nobel Prize winner Dr. Lee Hartwell to lead major health initiative Archived September 29, 2009, at the Wayback Machine Biodesign Institute News
- ^ "Amrita News: Nobel-prize winner is adjunct faculty at Amrita". October 6, 2011.
- ^ "Lee Hartwell Lectures".
External links
- Leland H. Hartwell on Nobelprize.org
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