Lentinan
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Molar mass | ~ 500,000 Da |
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Lentinan is a
fruit body of shiitake
mushroom (Lentinula edodes).
Chemistry
Lentinan is a β-1,3 beta-glucan with β-1,6 branching. It has a molecular weight of 500,000 Da and specific rotation of +14-22° (NaOH).
Research
Preclinical studies
An
Human clinical trials
Lentinan has been the subject of a limited number of clinical studies in cancer patients in Japan;[3][4][5][6][7][8][9][10] however, evidence of efficacy is lacking.[11][12]
Adverse effects
Lentinan has been reported to cause shiitake mushroom dermatitis.[13]
See also
- Medicinal mushrooms