Leukapheresis
Leukapheresis | |
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ICD-10-PCS | 6A550Z1, 6A551Z1 |
MeSH | D007937 |
OPS-301 code | 8-802 |
Leukapheresis (/ˌluˈkʌfɜːriːsɪs/ ⓘ) is a laboratory procedure in which white blood cells are separated from a sample of blood. It is a specific type of apheresis, the more general term for separating out one particular constituent of blood and returning the remainder to the circulation.
Leukapheresis may be performed to decrease a very high white blood cell count, to obtain blood cells from a patient (
In the case of hematological malignancies such as chronic
Leukapheresis may be performed to obtain the patient's own blood cells for a later transplant. White blood cells may be removed to protect them from damage before high-dose chemotherapy, then transfused back into the patient, in the treatment of advanced breast cancer.[1] Another novel use of cells obtained through leukapheresis is to stimulate a patient’s immune system to target prostate cancer cells.[2]
Alternatively, only
where these cells play an active part in the inflammation process.Leukapheresis, typically for granulocytes, is a rarely performed
Leukapheresis is used in evolving
Etymology
The word leukapheresis (
References
- ^ Transfusion. 2003 Feb;43(2):259-64. Leukapheresis after high-dose chemotherapy and autologous peripheral blood progenitor cell transplantation: a novel approach to harvest a second autograft. Schwella N, Braun A, Ahrens N, Rick O, Salama A.
- S2CID 12168204.)
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: CS1 maint: multiple names: authors list (link - National Institute for Health and Clinical Excellence, Leukapheresis for inflammatory bowel disease[permanent dead link] (guidance). Retrieved Oct. 06 2005
- PMID 8450066.
- ^ "Neutropenia". The Lecturio Medical Concept Library. Retrieved 15 August 2021.