Lines of Zahn
Lines of Zahn | |
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erythrocytes. | |
Specialty | Pathology |
Causes | Thrombosis |
Lines of Zahn are a characteristic of thrombi. They have layers, with lighter layers of platelets and fibrin, and darker layers of red blood cells. They are more present on thrombi formed with faster blood flow, more so on thrombi from the heart and aorta. They are only seen on thrombi formed before death. They are named after German–Swiss pathologist Friedrich Wilhelm Zahn.
Definition
Lines of Zahn are a characteristic of
Evaluation
Lines of Zahn can be used to confirm diagnosis of a thrombus.
History
Lines of Zahn are named after German–Swiss pathologist Friedrich Wilhelm Zahn.[6]
Additional images
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Thrombus showing circumferential lines of Zahn.
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Low magnification micrograph showing laminations in a thrombus in a fatal pulmonary embolism. H&E stain.
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Intermediate magnification micrograph showing laminations in a thrombus in a fatal pulmonary embolism. H&E stain.
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High magnification micrograph showing laminations in a thrombus in a fatal pulmonary embolism. H&E stain.
References
Further reading
- Kumar V, Abbas AK, Fausto N (2005). Robbins & Cotran Pathologic Basis of Disease (7th ed.). Pennsylvania: Elsevier/Saunders. ISBN 978-0-7216-0187-8.
- Cross SS, ed. (2013). "Chapter 6: Thrombosis, Embolism and Infarction". Underwood's pathology : a clinical approach (PDF) (6th ed.). Edinburgh: Churchill Livingstone. ISBN 978-0-7020-4672-8.