Lipophilicity
(Redirected from
Lipophilic
)Lipophilicity (from
hydrophilic
("water-loving") substances tend to dissolve in water and other hydrophilic substances.
Lipophilicity, hydrophobicity, and non-polarity may describe the same tendency towards participation in the
fluorocarbons, which are hydrophobic but not lipophilic.[citation needed
]
Surfactants
Micelles draw oily substances into their hydrophobic cores, explaining the basic action of soaps and detergents used for personal cleanliness and for laundering clothes. Micelles are also biologically important for the transport of fatty substances in the small intestine surface in the first step that leads to the absorption of the components of fats (largely fatty acids and 2-monoglycerides).[citation needed
]
Cell membranes are bilayer structures principally formed from
phospholipids, molecules which have a highly water interactive, ionic phosphate head groups attached to two long alkyl tails.[citation needed
]
By contrast,
detergents because fluorocarbons are not lipophilic.[citation needed
]
Oxybenzone, a common cosmetic ingredient often used in sunscreens, penetrates the skin particularly well because it is not very lipophilic.[3] Anywhere from 0.4% to 8.7% of oxybenzone can be absorbed after one topical sunscreen application, as measured in urine excretions.[4]
See also
References
- Compendium of Chemical Terminology, lipophilic, accessed 15 Jan 2007.
- ISBN 978-0-7637-0432-2.
- ^ Hanson KM, Gratton E, Bardeen CJ. (2006). "Sunscreen enhancement of UV-induced reactive oxygen species in the skin". Free Radical Biology & Medicine 41(8): 1205–1212
- ^ H. Gonzalez, H., Farbrot, A., Larko. O., and Wennberg, A. M. (2006). "Percutaneous absorption of the sunscreen benzophenone-3 after repeated whole-body applications, with and without ultraviolet irradiation". British Journal of Dermatology, 154:337–340.