Lipotropin
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Lipotropin is the name for two
β-Lipotropin
β-Lipotropin is a 90-
β-Lipotropin can be cleaved into smaller peptides. In humans, γ-lipotropin,
γ-Lipotropin
γ-lipotropin is the amino-terminal peptide fragment of β-lipotropin. In humans, it has 56 amino acids. Gamma lipotropin is identical to the first 56 amino acid sequences of β-lipotropin. It can be cleaved to β-melanocyte stimulating hormone.
In sheep, gamma-lipotropic hormone is a 58-amino-acid long pituitary polypeptide formed from the first 58 residues of beta-lipotropic hormone. The
Use in pain relief
β-endorphin has been determined to have an analgesic effect. It produces effects similar to or characteristic of morphine.[5]
Use in sport
Lipotropin is on the Prohibited List of substances by the World Anti Doping Agency.
Clinical trials
In 2020 AOD-9604 underwent clinical trials into its use for the treatment of pain.[10]
References
- PMID 1063395.
- PMID 6956916.
- PMID 1064883.
- PMID 1276982.
- PMID 26903509.
- ^ "The Prohibited List". World Anti Doping Agency. Retrieved 2023-11-15.
- ^ Peptides Direct information page, accessed 26 August 2013
- )
- ^ Dillon A (13 August 2013). "Statement of Charges against James Hird and Essendon Football Club" (PDF). Australian Football League. Archived from the original (PDF) on 2013-09-03. Retrieved 26 August 2013.
- ^ "Lateral Pharma | LAT8881". Retrieved 2021-03-27.
External links
- beta-Lipotropin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- gamma-Lipotropin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)