Lobomycosis
| Lobo's disease | |
|---|---|
| Other names | Lobo disease, Lacazia loboi[1] |
Lobomycosis is a fungal infection of the skin.[4] It usually presents with bumps in the skin, firm swellings, deep skin lesions, or malignant tumors.[1]
It is caused by Lacazia loboi (formerly named Loboa loboi).[5] Transmission is generally by direct contact with contaminated water, soil, vegetation, or by direct contact with an infected dolphin.[1]
Diagnosis is by identifying Lacazia laboi in a lesion.[1]
This disease is usually found in humans[6] and bottlenose dolphins, with the possible risk of transmission from one species to the other.[7]
It was discovered by
Signs and symptoms
The disease is
Diagnosis of Lobo's disease is made by taking a sample of the infected skin (a skin biopsy) and examining it under the microscope. Lacazia loboi is characterized by long chains of spherical cells interconnected by tubules. The cells appear to be yeast-like with a diameter of 5 to 12 μm. Attempts to culture L. loboi have so far been unsuccessful.[10]
Diagnosis
Differential diagnosis
The disease is often misdiagnosed as
Treatment
Surgical excision or
Other animals
Lesions in dolphins occur on the dorsal fin, head,
See also
- List of cutaneous conditions
References
- ^ a b c d e "ICD-11 - ICD-11 for Mortality and Morbidity Statistics". icd.who.int. Retrieved 7 July 2021.
- S2CID 205394764.
- PMID 17959227.
- ^ ISBN 978-0-7020-6830-0.
- ^ Honda, Kord; Horner, Kyle (2006). "Lobomycosis". eMedicine. Retrieved 2007-01-18.
- PMID 15200867.
- PMID 23919604.
- ^ Valdebran, Manuel (14 April 2017). "Lobomycosis: Background, Pathophysiology, Epidemiology". Medscape. WebMD. Retrieved 17 September 2021.
- ^ Baruzzi RG, Lacaz CS, Souza FA (1979). "História natural da doença de Jorge Lobo. Ocorrência entre os índios Caibi (Brasil Central)". Rev Inst Med Trop Sao Paulo. 21: 302–338.
- ^ PMID 35628750.
- ISBN 978-1-4160-2999-1.
- PMID 19220901.
- PMID 16426180.
Further reading
- Bermudez, L., M.F. van Bressem, O. Reyes-Jaimes, A.J. Sayegh & A.E. Paniz Mondolfi (2009) Lobomycosis in man and lobomycosis-like disease in bottlenose dolphin, Venezuela. Emerg. Infect. Dis., 15: 1301–1303.
- Carvalho, K. A. D., Floriano, M. C., Enokihara, M. M. S., & Mascarenhas, M. R. M. (2015). Jorge Lobo’s disease. Anais brasileiros de dermatologia, 90(4), 586–588.
- Esperon, F., D. Garcia-Parraga, E.N. Belliere & J.M. Sanchez-Vizcaino (2012) Molecular diagnosis of lobomycosis-like disease in a bottlenose dolphin in captivity. Med. Mycol., 50: 106–109.
- Francesconi, V. A., Klein, A. P., Santos, A. P. B. G., Ramasawmy, R., & Francesconi, F (2014) Lobomycosis: epidemiology, clinical presentation, and management options. Therapeutics and Clinical Risk Management, 10, 851.
- Rodríguez-Toro G (May 1993). "Lobomycosis". Int. J. Dermatol. (Review). 32 (5): 324–32. S2CID 221814305.
- Paniz-Mondolfi, A., C. Talhari, L.S. Hoffmann, D.L. Connor and S. Talhari & al. (2012) Lobomycosis: An emerging disease in humans and delphinidae. Mycoses, 55: 298-309 | résumé.
- Reif, J.S., A.M. Schaefer & G.D. Bossart (2013) Lobomycosis: Risk of zoonotic transmission from dolphins to humans. Vector Borne Zoonotic Dis., 13: 689–693.
- Schaefer, A. M., Reif, J. S., Guzmán, E. A., Bossart, G. D., Ottuso, P., Snyder, J., ... & McCarthy, P. J. (2016). Toward the identification, characterization and experimental culture of Lacazia loboi from Atlantic bottlenose dolphin (Tursiops truncatus). Sabouraudia, 54(6), 659–665.