Lymphocytopenia
Lymphocytopenia | |
---|---|
Other names | Lymphopenia |
Specialty | Hematology, immunology |
Lymphocytopenia is the condition of having an abnormally low level of
Lymphocytopenia may be present as part of a pancytopenia, when the total numbers of all types of blood cells are reduced.
Classification
In some cases, lymphocytopenia can be further classified according to which kind of lymphocytes are reduced. If all three kinds of lymphocytes are suppressed, then the term is used without further qualification.
- In T lymphocytopenia, there are too few AIDS), but may be Idiopathic CD4+ lymphocytopenia (ICL), which is a very rare heterogeneous disorder defined by CD4+ T-cell counts below 300 cells/μL in the absence of any known immune deficiency condition, such as human immunodeficiency virus (HIV) infection or chemotherapy.[2]
- In B lymphocytopenia, there are too few B lymphocytes, but possibly normal numbers of other lymphocytes. It causes, and manifests as, a humoral immune deficiency. This is usually caused by medications that suppress the immune system.[citation needed]
- In NK lymphocytopenia, there are too few natural killer cells, but normal numbers of other lymphocytes. This is very rare.[citation needed]
Causes
The most common cause of temporary lymphocytopenia is a recent infection, such as the common cold.[citation needed]
Lymphocytopenia, but not idiopathic
Lymphocytopenia is a frequent, temporary result from many types of
also cause lymphocytopenia.Another cause is infection with
Large doses of
Diagnosis
Lymphocytopenia is diagnosed when the complete blood count shows a lymphocyte count lower than the age-appropriate reference interval (for example, below 1.0 x 10(9)/L in an adult).[citation needed]
Prognosis
Lymphocytopenia that is caused by infections tends to resolve once the infection has cleared. Patients with idiopathic CD4+ lymphocytopenia may have either abnormally low but stable CD4+ cell counts, or abnormally low and progressively falling CD4+ cell counts; the latter condition is terminal.[citation needed]
Other animals
Lymphocytopenia caused by
References
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- ^ Low, Donald (2004). "Sars: Lessons from Toronto". Learning from SARS: Preparing for the Next Disease Outbreak: Workshop Summary. National Academies Press (US). pp. 63–71.
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- ^ "The Science Behind LTCI | Treatment for Cats with FIV and FeLV". Archived from the original on 2013-07-02. Retrieved 2013-03-20.