Mòjiāng virus

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Mòjiāng virus
Structure of MojV-G glycoprotein
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum:
Negarnaviricota
Class: Monjiviricetes
Order: Mononegavirales
Family: Paramyxoviridae
Genus: Henipavirus
Species:
Mojiang henipavirus
Synonyms
  • Mòjiāng Paramyxovirus
  • Mòjiāng Henipa-like virus

Mòjiāng virus (MojV), officially Mojiang henipavirus, is a virus in the family Paramyxoviridae. Based on phylogenetics, Mòjiāng virus is placed in the genus Henipavirus or described as a henipa-like virus.[1] Antibodies raised against Mòjiāng virus glycoproteins are serologically distinct from other henipaviruses (among which higher cross-reactivity is observed).[2][3]

Discovery

In the spring of 2012, three miners working in an abandoned copper mine in

SARS-CoV2.[5]

Mammal species present in the cave, including

chiropterans, primarily Pteropus spp, MojV is the only henipavirus believed to be found primarily in rodents.[1]

Virology

The cell surface receptor for Mòjiāng virus remains unknown. Unlike all other known

CD150, in cell culture. MojV-G is the most divergent gene, with less than 50% sequence to HeV-G. This makes MojV-G as divergent from HNV-G as HNV-G is as divergent from the morbillivirus attachment glycoprotein.[3]

See also

  • RaTG13, a SARS-like betacoronavirus discovered in 2013 in bat droppings from a mining cave in Mojiang County

References

  1. ^ a b "Genus: Henipavirus - Paramyxoviridae - Mononegavirales". International Committee on Taxonomy of Viruses (ICTV). Retrieved 2020-05-07.
  2. PMID 32340278
    .
  3. ^
    PMID 28699636
    .
  4. ^ Stone, Richard (20 March 2014). "A New Killer Virus in China?". Science. Retrieved 11 June 2022.
  5. PMID 33199918
    .
  6. PMID 24865545
    .
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