MAPK1

Source: Wikipedia, the free encyclopedia.
MAPK1
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_138957
NM_002745

NM_001038663
NM_011949
NM_001357115
NM_028991

RefSeq (protein)

NP_002736
NP_620407

NP_001033752
NP_036079
NP_001344044

Location (UCSC)Chr 22: 21.76 – 21.87 MbChr 16: 16.8 – 16.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mitogen-activated protein kinase 1 (MAPK 1), also known as ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.[5]

Function

The protein encoded by this gene is a member of the

UTRs, have been reported for this gene.[6] MAPK1 contains multiple amino acid sites that are phosphorylated and ubiquitinated.[7]

Interactions

MAPK1 has been shown to

interact
with:

Clinical significance

Mutations in MAPK1 are implicated in many types of cancer.[46]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100030 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063358 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. PMID 1540184
    .
  6. ^ "Entrez Gene: MAPK1 mitogen-activated protein kinase 1".
  7. ^ "ERK2 (human)". www.phosphosite.org. Retrieved 2020-10-31.
  8. PMID 12058067
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  46. ^ "Expression of MAPK1 in cancer - Summary - The Human Protein Atlas". www.proteinatlas.org.

Further reading

External links

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