On March 6, 1978, Televizija Skopje started broadcasting its Second Program. It broadcast once a week, every Monday, and later in the middle of the week, for four hours, in full color. The second program was alternative and complementary to the first, with shows from all genres that are prepared in both sectors for informative-documentary and cultural-artistic shows. The editor-in-chief of the Second Program was Zoran Vangelov. Otherwise, on other days and at the time when it did not broadcast its own content, the second channel broadcast live programs from other Yugoslav television centers.
Since 1994, the channel broadcasts a schedule aiming towards the minority communities of the Republic of North Macedonia. It broadcasts programs in Albanian, Turkish, as well as programs in Serbian, Romani, Vlach and Bosnian.
From 2020, MRT 2 the channel started broadcasting exclusively in Albanian. All other programs in minority languages moved to a new channel, MRT 4.
