Manidipine

Source: Wikipedia, the free encyclopedia.
Manidipine
Clinical data
Trade namesManyper, Caldine, etc.
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • (±)-2-[4-(Diphenylmethyl)piperazin-1-yl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
JSmol)
  • [O-][N+](=O)c1cccc(c1)C5C(/C(=O)OC)=C(\N\C(=C5\C(=O)OCCN4CCN(C(c2ccccc2)c3ccccc3)CC4)C)C
  • InChI=1S/C35H38N4O6/c1-24-30(34(40)44-3)32(28-15-10-16-29(23-28)39(42)43)31(25(2)36-24)35(41)45-22-21-37-17-19-38(20-18-37)33(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-16,23,32-33,36H,17-22H2,1-3H3

Manidipine is a

antihypertensive.[1][2][3][4][5]

It was patented in 1982 and approved for medical use in 1990.[6]

References

  1. ^ Cheer SM, McClellan K (2001). "Manidipine: a review of its use in hypertension". Drugs. 61 (12): 1777–1799.
    S2CID 260814599. Archived from the original
    on 2013-01-17. Retrieved 2009-06-20.
  2. ^ McKeage K, Scott LJ (2004). "Manidipine: a review of its use in the management of hypertension". Drugs. 64 (17): 1923–1940.
    S2CID 195689527. Archived from the original
    on 2013-01-16. Retrieved 2009-06-20.
  3. ^ Roca-Cusachs A, Triposkiadis F (2005). "Antihypertensive effect of manidipine". Drugs. 65 (Suppl 2): 11–19.
    S2CID 25854593. Archived from the original
    on 2013-01-16. Retrieved 2009-06-20.
  4. PMID 17703633
    .
  5. doi:10.1016/S0011-393X(05)80475-8
    .
  6. ISBN 9783527607495
    .