Mark E. Davis

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Mark E. Davis
BornOctober 14, 1955
Chemical Engineering
InstitutionsCalifornia Institute of Technology
Doctoral advisorJohn Yamanis

Mark E. Davis is the Warren and Katherine Schlinger

Chemical Engineering at the California Institute of Technology. He is a member of the City of Hope National Medical Center. He earned his B.S., M.S., and Ph.D. in chemical engineering all from the University of Kentucky. His lab focuses on the synthesis of materials for catalysis and biocompatible materials for drug delivery.[2]

Davis was elected as a member into the National Academy of Engineering in 1997, for pioneering work in the synthesis of new catalytic materials.

Research

He did his doctoral work with John Yamanis on reactions engineering with annular bed reactors. His academic career started as an assistant professor at

molecular sieves and increasing the pore size.[3][4] In 1991, he joined the faculty of the California Institute of Technology and served as the Executive Officer of the department from 1999 to 2004. In 2004 he joined the City of Hope National Medical Center, Comprehensive Cancer Center.[5]

In 1995, his wife, Mary, was diagnosed with breast cancer and had to go through chemotherapy. Having seen the side effects of cancer treatment, he decided to do research on molecules that would prevent drug from leaking through healthy blood vessels but would stop at the tumor. His group conjugated cyclodextrin to the anti-cancer compound camptothecin to improve the bio-availability and exhibit efficacy in mouse tumor models.[6] The compound, CRLX101 is now being tested in clinical trials.[7] The cyclodextrin nanoparticles are also being used to encapsulate siRNA.

He was the recipient of the Alan T. Waterman Award in 1990. In 1997, he was elected to the National Academy of Engineering, in 2006, to the National Academy of Sciences, and in 2011, the National Academy of Medicine.[8] He is also the founder of Insert Therapeutics and Calando Pharmaceuticals.

Personal

Mark was born in Ellwood City, Pennsylvania, as the son of teachers of history and English.[5] Mark Davis is an accomplished athlete and was on a full scholarship in track and field at the

flautist before being diagnosed with breast cancer.[5]

References

  1. ^ "Avelino Corma Canós, Mark E. Davis and Galen D. Stucky, Prince of Asturias Award for Technical and Scientific Research - Communication".
  2. ^ "Mark E. Davis". Caltech. Archived from the original on 14 April 2019. Retrieved 7 April 2013.
  3. S2CID 34932513
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  4. S2CID 26623258
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  5. ^
    PMID 18093958
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  6. PMID 16533788
    .
  7. ^ a b Gellene, Denise (11 August 2007). "Science begins at home". LA Times. Retrieved 7 April 2013.
  8. ^ "Professor Mark E Davis".
  9. ^ Fesenmaier, Kimm (28 July 2011). "Caltech Professor Runs to Victories on the World Stage". Caltech News. Retrieved 7 April 2013.

External links

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