Martin Kamen

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Martin David Kamen (August 27, 1913,

University of California Radiation Laboratory, Berkeley.[1] He also confirmed that all of the oxygen released in photosynthesis comes from water, not carbon dioxide, in 1941.[2][3]

Kamen was the first to use carbon-14 to study a biochemical system, and his work revolutionized biochemistry and molecular biology, enabling scientists to trace a wide variety of biological reactions and processes.

Enrico Fermi award for lifetime scientific achievement.[7][4]

Early life and education

Kamen was born on August 27, 1913, in

Jewish immigrants.[8][9] He grew up in Chicago. Interested in classical music, he initially entered the University of Chicago as a music student before changing his major from music to chemistry. Although he gave up music as a career, Kamen continued to play the viola at a high professional level during the rest of his life.[1]

Kamen received a

William D. Harkins on "Neutron-Proton Inter-action: The Scattering of Neutrons by Protons."[1][10]

Career

From 1936 to 1944, Kamen worked at the Radiation laboratories at the University of California, Berkeley.[10] Kamen gained a research position in chemistry and nuclear physics under Ernest Lawrence by working without pay for six months, until he was hired to oversee the preparation and distribution of the cyclotron's products.[10][1] Kamen's major achievements during his time at Berkeley included the co-discovery of the synthesis of carbon-14 with Sam Ruben in 1940, and the confirmation that all of the oxygen released in photosynthesis comes from water, not carbon dioxide, in 1941.[1][3]

From 1941 to 1944, Kamen and others at the Berkeley Radiation Laboratory worked on the Manhattan Project.[11] In 1943, Kamen was assigned to Manhattan Project work at Oak Ridge, Tennessee, where he worked briefly before returning to Berkeley.[12] In spite of the fact that his scientific capabilities were unquestioned,

nuclear weapons secrets to the Soviet Union (which at the time was allied with the US and others against Nazi Germany).[13]

Kamen was unable to obtain another academic position until 1945 when he was hired by

Arthur Holly Compton to run the cyclotron program in the medical school of Washington University in St. Louis. Kamen taught the faculty how to use radioactive tracer materials in research, and continued to develop his interests in biochemistry.[1][14] His book Isotopic Tracers in Biology (1947) became a standard text on tracer methodology and highly influenced tracer use in biochemistry.[15]

In 1957, Kamen moved to

Nathan Oram Kaplan to establish the Graduate Department of Biochemistry.[1][16]
In 1961 Kamen joined the University of California, San Diego, where he founded a biochemistry group as part of the university's new department of chemistry.[1] Kamen remained at the University of California, San Diego, retiring from teaching (but not research) to become an emeritus professor in 1978.[14][5]

Martin Kamen died August 31, 2002, at the age of 89 in Montecito (Santa Barbara), California.[9]

Research

Although carbon-14 was previously known, the discovery of the synthesis of carbon-14 occurred at Berkeley in 1940 when Kamen and Sam Ruben bombarded graphite in the cyclotron in hopes of producing a radioactive isotope of carbon that could be used as a tracer in investigating chemical reactions in photosynthesis. Their experiment resulted in production of carbon-14.[5][17][8] By bombarding matter with particles in the

radioactive isotopes such as carbon-14 were generated. Using carbon-14, the order of events in biochemical reactions could be elucidated, showing the precursors of a particular biochemical product, revealing the network of reactions that constitute life.[18]

Kamen confirmed in 1941 that all of the

tumors,[19] making substantial contributions.[14]

Security risk controversy

Kamen came under long-term suspicion of espionage activity as a result of two incidents in 1944. He has described his experiences during this era in his autobiography, Radiant Science, Dark Politics. He first aroused suspicion while working at Oak Ridge.

radioactive sodium for an experiment, and Kamen was surprised that the resulting sodium had a purple glow, indicating it was much more intensely radioactive than could be produced in a cyclotron. Kamen recognized immediately that the sodium must have been irradiated in a nuclear reactor elsewhere in the facility. Because of wartime secrecy, he had not been aware of the reactor's existence. He excitedly told Ernest O. Lawrence about his discovery, in the hearing of Lawrence's Army escort. Shortly thereafter, an investigation was launched to find out who had leaked the information to Kamen.[12][5]

A surveillance photograph of Kheifets, Kamen and Kasparov

After returning to Berkeley, Kamen met two Russian officials at a party given by his friend, the violinist

FBI agents observed the dinner, on July 1, 1944, took a photograph of the men together, and submitted a report alleging Kamen to have discussed atomic research with Kheifets.[13][5][20] In a memorandum of July 11, 1944, Army officials ordered Lawrence to have Martin Kamen dismissed from his Berkeley position and his work on the Manhattan Project on suspicion of being a “security risk.” There was no hearing or method of appeal.[13][21][22]

In addition,

Ruth B. Shipley at the Passport Division of the State Department revoked Kamen's passport in 1947, and repeatedly refused to reissue it. This had significant negative effects on Kamen's career and research, preventing him from traveling abroad to give lectures, attend conferences, and take up visiting professorships.[23]
In 1948, the
House Committee on Un-American Activities summoned Kamen to testify about his dinner conversation of 1944.[24] From 1947-1955 Kamen engaged in repeated attempts to regain his passport and to engage in international scientific activities. He sought legal counsel in 1950, and started litigation to regain his passport and right to travel, gaining support from the Federation of American Scientists, the American Civil Liberties Union and others.[21]

In 1951 the

blacklisted as a security risk.[25] He was finally able to regain his passport as of July 9, 1955.[26]

Awards and honors

Kamen was elected a Fellow of the American Physical Society in 1941.[27] He became a fellow of the American Academy of Arts and Sciences in 1958.[28] In 1962, Kamen was elected as a member of the National Academy of Sciences.[29] He was elected to the American Philosophical Society in 1974.[30]

Kamen became a Guggenheim Fellowship recipient in 1956 and again in 1972, in the field of Molecular and Cellular Biology.[31] Kamen was awarded the Charles F. Kettering Award for Excellence in Photosynthesis Research from the

American Society of Biological Chemists in 1982.[33]
He received the 1989 Albert Einstein World Award of Science.[15] On April 24, 1996, he was presented with the 1995 Enrico Fermi Award, given by the U.S. President and the Department of Energy for lifetime scientific achievement.[12][7] Some believe he should have won a Nobel Prize,[34] for which he was nominated 14 times between 1955 and 1970.[35]

Books

  • Kamen, Martin D. (1947). Radioactive Tracers in Biology: An Introduction to Tracer Methodology (1st ed.). New York: Academic Press.[36][37]
  • Kamen, Martin David (1963). Primary processes in photosynthesis. New York: Academic Press.
    ISBN 9781483274454.[38]
  • Kamen, Martin D. (1964). A Tracer Experiment: Tracing Biochemical Reactions with Radioisotopes. New York: Holt Rinehart Winston.[39][40]
  • Kamen, Martin David (1985). Radiant science, dark politics : a memoir of the nuclear age. Berkeley: University of California Press.
    Edwin M. McMillan
    .

Archival Collections

References

  1. ^
    doi:10.1063/1.1583542
    .
  2. ^
    ISBN 978-81-209-0496-5
    . Retrieved August 12, 2022.
  3. ^
    ISBN 978-94-017-9582-1
    . Retrieved August 12, 2022.
  4. ^ a b Lytle, James (January 8, 1996). "Groundbreaking chemist receives Enrico Fermi Award". USC News. Retrieved August 15, 2022.
  5. ^ a b c d e f Wright, Pierce (September 9, 2002). "Martin Kamen". The Guardian. Retrieved December 26, 2019.
  6. ^ "Martin David Kamen Papers". University of California, San Diego. Retrieved August 15, 2022.
  7. ^ a b "FERMI Martin D. Kamen, 1995 | U.S. DOE Office of Science (SC)". US Department of Energy. December 28, 2010. Retrieved August 15, 2022.
  8. ^
    PMID 3090931
    .
  9. ^ a b Maugh, Thomas H (September 6, 2002). "Martin D. Kamen, 89; Scientist Who Discovered the Element Carbon-14". Los Angeles Times.
  10. ^
    PMC 2988396
    .
  11. ^ a b The Shameful Years: Thirty Years of Soviet Espionage in the United States (PDF). U.S. Congress, House of Representatives, Committee on Un-American Activities. December 30, 1951. pp. 39–40. Retrieved August 15, 2022.
  12. ^ a b c d Chang, Kenneth (September 5, 2002). "Martin D. Kamen, 89, a Discoverer of Radioactive Carbon-14". The New York Times. Retrieved August 15, 2022.
  13. ^
    ISBN 978-0-226-01794-5
    . Retrieved August 12, 2022.
  14. ^
    S2CID 235744943
    . Retrieved August 15, 2022.
  15. ^ a b "Albert Einstein World Award of Science 1989". November 8, 1989. Retrieved December 26, 2019.
  16. ^ "University of California: In Memoriam, 1987". University of California Regents. 1987. Retrieved August 15, 2022.
  17. S2CID 5780582
    .
  18. ISBN 978-3-030-31688-4
    . Retrieved August 15, 2022.
  19. ^ "Carbon-14 discoverer who was harassed as communist". The Irish Times. September 21, 2002. Retrieved August 15, 2022.
  20. ^ Report of January 11, 1944, FBI Silvermaster File, serial 3378
  21. ^ a b "Register of Martin David Kamen Papers - MSS 0098". library.ucsd.edu. Retrieved August 12, 2022.
  22. ^ "In Memoriam: Martin David Kamen Professor Emeritus of Chemistry UC San Diego 1913-2002". University of California Senate. Retrieved August 12, 2022.
  23. JSTOR 793677
    . Retrieved August 15, 2022.
  24. ^ United States Congress House Committee on Un-American Activities (September 28, 1948). US House of Representatives, 80th Congress, Special Session, Committee on Un-American Activities, Report on Soviet Espionage Activities in Connection with the Atom Bomb. US Gov. Printing Office. pp. 181–182.
  25. ^ "Martin Kamen". Atomic Heritage Foundation. Retrieved August 12, 2022.
  26. JSTOR 3478757
    . Retrieved August 15, 2022.
  27. ^ "APS Fellow Archive". American Physical Society. (search on year 1941 and institution University of California)
  28. ^ "Fellows of the American Academy of Arts and Sciences" (PDF). American Academy of Arts and Sciences. Retrieved December 26, 2019.
  29. ^ "Martin D. Kamen". National Academy of Sciences. Retrieved December 26, 2019.
  30. ^ "APS Member History". search.amphilsoc.org. Retrieved August 4, 2022.
  31. ^ "Martin D. Kamen". John Simon Guggenheim Foundation. Retrieved December 26, 2019.
  32. ^ "Charles F. Kettering Award". American Society of Plant Biologists. Retrieved August 15, 2022.
  33. ^ "ASBMB–Merck Award". American Society of Biological Chemists. Retrieved August 15, 2022.
  34. ^ Govindjee; Blankenship, Robert E. (2018). "Martin D. Kamen, Whose Discovery of 14 C Changed Plant Biology as Well as Archaeology" (PDF). Plantae.
  35. ^ "Nomination archive". The Nobel Prize. April 1, 2020. Retrieved August 16, 2022.
  36. ISSN 0036-8075
    .
  37. S2CID 33381222
    .
  38. S2CID 239836849
    . Retrieved August 15, 2022.
  39. JSTOR 4441301
    .
  40. ISSN 0021-9584
    .
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