Master regulator gene
(Redirected from
Master regulator
)In
cell fate and differentiation
.
Examples
Most genes considered master regulators code for
Twist transcription factor.[2]
Other genes reported as master regulators code for
noncoding RNAs.[4]
Criticism
The master regulator concept has been criticized for being a "simplified paradigm" that fails to account for the multifactorial influences on some cell fates.[5]