Meclofenoxate

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Meclofenoxate
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)[1]
  • US: Not FDA approved
  • In general: ℞ (Prescription only)
Identifiers
  • 2-Dimethylaminoethyl (4-chlorophenoxy)acetate
JSmol)
  • Clc1ccc(cc1)OCC(=O)OCCN(C)C
  • InChI=1S/C12H16ClNO3/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11/h3-6H,7-9H2,1-2H3 ☒N
  • Key:XZTYGFHCIAKPGJ-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Meclofenoxate (

INN, BAN; brand name Lucidril, also known as centrophenoxine) is a cholinergic nootropic used as a dietary supplement.[2][3][4] It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid
(pCPA).

In elderly patients, meclofenoxate has been shown to improve performance on certain memory tests.[5] Meclofenoxate also increases cellular membrane phospholipids.[citation needed] It is sold in Japan and some European countries, such as Germany, Hungary, and Austria, as a prescription drug.

Side effects

Meclofenoxate is considered to be safe and high in

overdosage
and may indicate the need for the dosage to be reduced.

Research

Meclofenoxate, as well as DMAE, have been found to increase the lifespans of mice by 26.5%.[6][7]

Brand names

In addition to Lucidril, meclofenoxate has also been marketed under the brand names Amipolen, Analux, Brenal, Cellative, Centrophenoxin, Cerebron, Cerutil, Closete, Helfergin, Lucidryl, Lutiaron, Marucotol, Proserout, Proseryl, and Ropoxyl.[8] In the US, meclofenoxate is sold as a dietary supplement, although it is an unapproved drug.[4]

See also

References

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
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