Median eminence

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Median eminence
Median eminence is 'ME', at bottom-center, in light-green
Details
Identifiers
Latineminentia mediana hypothalami
MeSHD008473
NeuroNames402
NeuroLex IDbirnlex_925
TA98A14.1.08.409
TA25784
FMA74634
Anatomical terms of neuroanatomy

The median eminence is generally defined as the portion of the ventral hypothalamus from which the portal vessels arise.[1] The median eminence is a small swelling on the tuber cinereum, posterior to and atop the pituitary stalk; it lies in the area roughly bounded on its posterolateral region by the cerebral peduncles, and on its anterolateral region by the optic chiasm.

As one of the seven areas of the brain devoid of a

circumventricular organ having permeable capillaries.[3][4][5][6] Its main function is as a gateway for release of hypothalamic hormones,[7] although it does share contiguous perivascular spaces with the adjacent hypothalamic arcuate nucleus, indicating a potential sensory role.[4][8]

Physiology

The median eminence is a part of the hypothalamus from which regulatory hormones are released.

pars nervosa (part of the posterior pituitary gland) is continuous with the median eminence of the hypothalamus via the infundibular stalk. Parvocellular neurosecretory cells from the hypothalamus terminate in the median eminence of the hypothalamus.[9]

The median eminence is the structure where secretions of the hypothalamus (releasing and inhibiting regulatory hormones, known as "hypophysiotropic hormones") collect before entering the portal system emptying into the general circulation.

ventromedial nucleus of the hypothalamus.[4][8]

References