Mepivacaine

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Mepivacaine
Clinical data
AHFS/Drugs.comConsumer Drug Information
MedlinePlusa603026
Pregnancy
category
ATC code
Identifiers
  • (RS)-N-(2,6-dimethylphenyl)- 1-methyl-piperidine-2-carboxamide
JSmol)
  • O=C(Nc1c(cccc1C)C)C2N(C)CCCC2
  • InChI=1S/C15H22N2O/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18) checkY
  • Key:INWLQCZOYSRPNW-UHFFFAOYSA-N checkY
  (verify)

Mepivacaine /mɛˈpɪvəkn/ is a local anesthetic[1] of the amide type. Mepivacaine has a reasonably rapid onset (less rapid than that of procaine) and medium duration of action (longer than that of procaine)[2][3] and is marketed under various trade names including Carbocaine and Polocaine.

Mepivacaine became available in the United States in the 1960s.

Mepivacaine is used in any infiltration and local anesthesia.

It is supplied as the hydrochloride salt of the

racemate,[4] which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties.[4]

Mepivacaine was originally synthesized in Sweden at the laboratory of

References

  1. .
  2. ^ "Procaine". go.drugbank.com. Retrieved 2023-06-27.
  3. ^ "Mepivacaine". go.drugbank.com. Retrieved 2023-06-27.
  4. ^
    S2CID 22363370
    .
  5. .

External links