Merbecovirus
Merbecovirus | |
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MERS-CoV: structure, attachment, viral entry , and genomic composition
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Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Pisuviricota |
Class: | Pisoniviricetes |
Order: | Nidovirales |
Family: | Coronaviridae |
Genus: | Betacoronavirus |
Subgenus: | Merbecovirus |
Species[1] | |
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Merbecovirus is a
Middle East respiratory syndrome–related coronavirus (MERS-CoV).[1] The viruses in this subgenus were previously known as group 2c coronaviruses.[2][3]
Structure
The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope in which the membrane (M), envelope (E) and spike (S) structural proteins are anchored.[4][5]
See also
- Embecovirus (group 2a)
- Sarbecovirus(group 2b)
- Nobecovirus (group 2d)
References
- ^ a b "Virus Taxonomy: 2018 Release". International Committee on Taxonomy of Viruses (ICTV). October 2018. Retrieved 24 January 2019.
- PMID 17121802.
See figure 2.
- PMID 30791586.
CoVs are classified into four genera, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Within Betacoronavirus, they can be further subclassified into lineages A, B, C and D [1]. In 2018, these four lineages were reclassified as subgenera of Betacoronavirus, and renamed as Embecovirus (previous lineage A), Sarbecovirus (previous lineage B), Merbecovirus (previous lineage C) and Nobecovirus (previous lineage D) [2]. In addition, a fifth subgenus, Hibecovirus, was also included (Figure 1) [2].
- PMID 9233431
- PMID 21994708.
The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus.