Metabolite

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Metabolites
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In biochemistry, a metabolite is an intermediate or end product of metabolism.[1] The term is usually used for

odorants, and pheromones
).

A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene exemplifies a primary metabolite produced large-scale by industrial microbiology.

A

antibiotics and pigments
such as resins and terpenes etc.

Some antibiotics use primary metabolites as precursors, such as

metabolic pathways
.

Examples of primary metabolites produced by industrial microbiology include:[2]

Class Example
Alcohol Ethanol
Amino acids
 Glutamic acid, aspartic acid
Nucleotides
 5' guanylic acid
Antioxidants
Isoascorbic acid
Organic acids
 Acetic acid, lactic acid
Polyols
 Glycerol
Vitamins
 B2

The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.

Metabolites from

pharmaceutical, form as part of the natural biochemical process of degrading and eliminating the compounds.[3]
The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Understanding how pharmaceutical compounds are
side effects of their metabolites is an important part of drug discovery.[4]

See also

References

  1. ^ Venes, Donald, ed. (1940). Taber's Cyclopedic Medical Dictionary (23 ed.). Philadelphia: F.A. Davis (published 2017). p. 1510.
    ISBN 9780803659407
    . Retrieved 16 March 2020. metabolite [...] Any product of metabolism.
  2. S2CID 21590956
    .
  3. ^ Harris, Edward D. "Biochemical Facts behind the Definition and Properties of Metabolites" (PDF). FDA.gov. United States Food and Drug Administration. Retrieved 28 April 2017.
  4. S2CID 720243
    .

External links

Look up metabolite in Wiktionary, the free dictionary.
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