Methiodide

In organic chemistry, a methiodide is a chemical derivative produced by the reaction of a compound with

R₃N + CH₃I → (CH₃)R₃N⁺I⁻

Whereas the parent amines are hydrophobic and often oily, methiodides, being salts, are somewhat hydrophilic and exhibit high melting points. Methiodides exhibit altered pharmacological properties as well.

Examples include:

• Cocaine methiodide, a charged
  blood brain barrier and enter the brain^[1]
• Bicuculline methiodide, a water-soluble form of bicuculline

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