Michael Rawlins

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This article is about the clinical pharmacologist. For the EastEnders character, see
Michael Rawlins (EastEnders)
.

FBPhS FMedSci
Rawlins in 2014
Born(1941-03-28)28 March 1941
Died1 January 2023(2023-01-01) (aged 81)
Education
Medical career
Profession
University of Newcastle upon Tyne
Chair of Committee on Safety of Medicines
In office
1993–1998
Chair of National Institute for Health and Care Excellence
In office
1999–2013
Chair of UK Biobank
In office
2012 – December 2019
Chair of the Medicines and Healthcare products Regulatory Agency
In office
1 December 2014 – September 2020

Sir Michael David Rawlins

University of Newcastle upon Tyne. During his medical career he chaired several executive agencies including the Committee on Safety of Medicines from 1993 to 1998, followed by the National Institute for Health and Care Excellence (NICE) for 14 years from its formation in 1999 and then the Medicines and Healthcare products Regulatory Agency (MHRA) for six years from 2014. From 2012 to 2014 he was president of the Royal Society of Medicine
.

Rawlins delivered several eponymous lectures during his medical career including the 2008

Knight Grand Cross of the Order of the British Empire
(GBE) in 2017.

Early life and education

Michael Rawlins was born in Shrewsbury, Shropshire on 28 March 1941.[1][2] His father was the Reverend Jack Rawlins, vicar of Northwood-on-Trent in Staffordshire, and his mother was Evelyn Daphne Douglas-Hamilton who following the death of his father later married a general practitioner.[3] He attended Uppingham School, Rutland, with David Li and left there in 1959.[4] In 1962 he graduated first class from University of London.[5] He obtained his medical degree from St Thomas' Hospital in 1965.[6]

Career

Rawlins completed his

University of Newcastle upon Tyne.[2] There, he delivered his inaugural lecture in 1974, on "Variability in Response to Drugs", and remained at Newcastle until 2006.[2]

From 1977 to 1983 he was a member of the National Committee on Pharmacology.[2] In 1980 he became a member of the Committee on Safety of Medicines and was appointed its chairman in 1993; a position he retained until 1998.[2] He was a member of the Committee on Toxicity from 1989 to 1992, and the Standing Group on Health Technology Assessment from 1993 to 1995.[2] In 1998, he was appointed chairman of the Advisory Council on the Misuse of Drugs and served it until 2008.[7]

Rawlins was chair of the

National Institute for Clinical Excellence (NICE) from its foundation in 1999 until April 2013.[2][7] There, one of his early roles was the decision not to approve wide use of Relenza for flu.[3] Earlier he had clarified the difference of cost-effectiveness from affordability.[8]

In 2010, he helped establish the

UK Parliament, supported by more than 40 MPs and peers.[9] From 2012 to 2019 he was chair of UK Biobank.[10][11] In November 2014 the Medicines and Healthcare Products Regulatory Agency (MHRA) announced the appointment of Rawlins as its new chair, succeeding Gordon Duff.[12][13] The appointment was renewed for a further three years in 2017.[14]

Eponymous lectures

Rawlins delivered several eponymous lectures at the RCP, including the Bradshaw Lecture in 1986.[15] In 1994 he gave the RCP's William Withering lecture.[16] In it, contrary to the widely held belief that digitalis would unlikely pass modern day licensing regulations, he said of Withering's 1785 An account of the foxglove and some of its medical uses ... "Its contents would do justice to an expert report accompanying a Product Licence application to the drug regulatory authority of any state in the European Union".[16] In 2006 he gave the RCP'S Samuel Gee Lecture.[15]

De Testimonio

In his 2008

randomised controlled trials (RCT) and he encouraged a range of methods to provide a more holistic evaluation.[17] The lecture called for abandoning hierarchy of evidence at a time when Rawlins headed NICE, the UK's main independent agency whose purpose was to assess scientific evidence of medical treatments.[18] The problem with RCTs, he stated, is that they are too generalised.[19] He pointed out that science includes the not so exact but important "judgement".[20] Rawlins quoted William Blake's observation .. "God forbid that truth should be confined to mathematical demonstration",[18]
and said in his lecture:

The notion that evidence can be reliably placed in hierarchies is illusory. Decision makers need to assess and appraise all the available evidence irrespective of whether it has been derived from randomized controlled trials or observational studies; and the strengths and weaknesses of each need to be understood if reasonable and reliable conclusions are to be drawn.[20]

According to philosopher

evidence based medicine held similar views to Rawlins, his [Worrall's] own philosophical work on evidence based medicine might not be required.[20]

Honours and awards

Rawlins became a Fellow of the RCP London in 1977, and 10 years later became Fellow of the

Academy of Medical Sciences in 1998.[5]

He was awarded the Hutchinson Medal in 2003, and the Galen Medal in 2010.[21] In 2012 he received the Prince Mahidol Award for his contribution to medicine.[22] Zenith Global Health awarded him their Lifetime Achievement Award in 2019.[23]

Rawlins was

Knight Grand Cross of the Order of the British Empire (GBE) in the 2017 Birthday Honours for services to the safety of medicines, healthcare, and innovation.[24]

Personal and family

In 1963 he married Elizabeth Hambly, a nurse; they divorced in 2005.[1] In 1981 he became the first chairman of the Newcastle upon Tyne SDP and played an active part in the founding and development of the new party.

Death

Rawlins died in Darlington from

University of Newcastle upon Tyne.[7] Rawlins is survived by his daughters Vicky, Lucy, and Suzannah, and eight grandchildren.[3]

Selected publications

Articles

Books

References

  1. ^ a b Ferry, Georgina (10 January 2023). "Sir Michael Rawlins obituary". The Guardian. Archived from the original on 12 January 2023. Retrieved 12 January 2023.
  2. ^
    ISBN 978-085484-118-9
    .
  3. ^
    S2CID 255441025
    .
  4. ^ "Who, what, where". OU Magazine (42): 6. 2014–2015. Retrieved 5 January 2023.
  5. ^ a b c d e f "Written statement of Sir Michael Rawlins". Infected blood enquiry, 24 March 2022
  6. ^ "Prof Sir Michael Rawlins – 2011 – Jewish medical association". jewishmedicalassociationuk.org. Archived from the original on 3 January 2023. Retrieved 3 January 2023.
  7. ^ a b c "Tributes paid following the death of founding NICE chairman Professor Sir Mike Rawlins | News | News". NICE. Archived from the original on 3 January 2023. Retrieved 3 January 2023.
  8. ISBN 0-415-33671-6
    .
  9. S2CID 205959363
    .
  10. ^ "Staff Profile - Executive and Governance Office - Newcastle University". www.ncl.ac.uk. Archived from the original on 4 January 2023. Retrieved 4 January 2023.
  11. ^ "Obituary: Professor Sir Michael Rawlins". The Royal Society of Medicine. Archived from the original on 4 January 2023. Retrieved 3 January 2023.
  12. ^ "UK medicines regulator appoints Michael Rawlins as chairman". The Pharmaceutical Journal. The Royal Pharmaceutical Society. 2 November 2014. Archived from the original on 4 January 2023. Retrieved 4 January 2023.
  13. ^ "Professor Sir Michael Rawlins appointed Chair of Medicines and Healthcare Products Regulatory Agency" (Press release). Medicines and Healthcare Products Regulatory Agency. 3 November 2014. Retrieved 20 December 2014.
  14. ^ "Professor Sir Michael Rawlins re-appointed Chair - GOV.UK". www.gov.uk. 8 August 2017. Archived from the original on 4 January 2023. Retrieved 27 March 2018.
  15. ^
    ISBN 978-1-86016-347-0
    .
  16. ^
    ISBN 978-1-86016-292-3
    .
  17. S2CID 245224872
    .
  18. ^
    ISBN 978-0-470-03235-0
    .
  19. PMID 23294526
    .
  20. ^
    ISBN 978-0-19-873261-7
    .
  21. ^ "Intra-Cellular Therapies Appoints Professor Sir Michael Rawlins to its Board of Director". 14 March 2013. Archived from the original on 7 January 2023. Retrieved 7 January 2023.
  22. ^ "The Annoucement [sic] for the Prince Mahidol Award 2012 | Royal Thai Embassy in Prague". thaiembassy.cz. Archived from the original on 4 January 2023. Retrieved 3 January 2023.
  23. ^ "Sir. Michael Rawlins To Receive Lifetime Achievements Award at Zenith Global Health 2019 – Zenith Global Awards". 3 August 2019. Archived from the original on 5 January 2023. Retrieved 5 January 2023.
  24. ^ "No. 61962". The London Gazette (Supplement). 17 June 2017. p. B7.
  25. ^ Volpe, Sam (5 January 2023). "Tributes to North East 'medical hero' who fought to protect patients". ChronicleLive. Retrieved 8 January 2023.

Further reading

External links
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