Microcosm: E. coli and the New Science of Life

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Microcosm: E. coli and the New Science of Life
LC Class
QR82.E6 Z56 2008
Preceded byThe Descent of Man: The Concise Edition (2007) 
Followed byThe Tangled Bank: An Introduction to Evolution (2009) 

Microcosm: E. coli and the New Science of Life is a 2008 book by science writer Carl Zimmer. The book presents an overview of genetics research and genetic engineering by telling the story about the Escherichia coli (E. coli) species of bacteria which is omnipresent in the mammalian gastrointestinal tract. The title Microcosm refers to the notion that insights derived from the study of a relatively simple, single-celled organism like E. coli play in describing the fundamental features of all terrestrial life, including humans.[1]

Overview

Microcosm explores the history of E. coli's role as a popular organism to study for researchers that has revealed how genes work and are regulated giving insight into evolution, behaviour and ecology.

biofilms.[4]

Evolution vs. Intelligent Design

The book makes the case that the flagellum and antibiotic resistance evolved and continue to evolve due to selection pressure.[3][2] Zimmer devotes considerable attention to phenotypic plasticity and natural selection in E. coli genesis and notes that selection can be powered by humans individually (e.g., by antibiotic administration), collectively (e.g., by large-scale industrial food production), or inadvertently (e.g., by acting as host to a microbial pathogen).[4] The book refutes the notion of intelligent design as the source of novel features of the organism, such as the flagellum that are capable of propelling E. coli, by exploring examples of more primitive, intermediate forms that, while useful, fall short of full utility of propulsion.

Though not a scientist himself, the acknowledgment section suggests that Zimmer’s theses have been vetted by multiple members of current E. coli researchers.[4]

Publication

Microcosm: E. coli and the New Science of Life was first published by Pantheon Books on May 6, 2008 in hardcover format. A Reprint edition in softcover was subsequently published in by Vintage Books in 2009.

References

  1. ^ Steven Novella (21 May 2008). "SGU Episode 148". www.theskepticsguide.org (Podcast). The Skeptics Guide to the Universe. Event occurs at 39:25. Retrieved 23 February 2019.
  2. ^ a b Peter Dizikes (29 June 2008). "E. Coli and You". The New York Times. Retrieved 23 February 2019.
  3. ^ a b Jon Turney (9 July 2008). "Microcosm: E.coli And The New Science Of Life, by Carl Zimmer". The Independent. Archived from the original on 2022-05-14. Retrieved 23 February 2019.
  4. ^
    PMC 2586741
    .