Medical error
The examples and perspective in this article deal primarily with the United States and do not represent a worldwide view of the subject. (December 2010) |
A medical error is a preventable
, or other ailment.Definitions
The word error in medicine is used as a label for nearly all of the clinical incidents that harm patients. Medical errors are often described as human preventable errors in healthcare.[1] Whether the label is a medical error or human error, one definition used in medicine says that it occurs when a healthcare provider chooses an inappropriate method of care, improperly executes an appropriate method of care, or reads the wrong CT scan. It has been said that the definition should be the subject of more debate. For instance, studies of hand hygiene compliance of physicians in an ICU show that compliance varied from 19% to 85%.[2][needs update] The deaths that result from infections caught as a result of treatment providers improperly executing an appropriate method of care by not complying with known safety standards for hand hygiene are difficult to regard as innocent accidents or mistakes.
There are many types of medical error, from minor to major,[3] and causality is often poorly determined.[4][needs update]
There are many taxonomies for classifying medical errors.[5]
Definitions of diagnostic error
There is no single definition of diagnostic error, reflecting in part the dual nature of the word diagnosis, which is both a noun (the name of the assigned disease; diagnosis is a label) and a verb (the act of arriving at a diagnosis; diagnosis is a process). At the present time, there are at least 4 definitions of diagnostic error in active use:
Graber et al. defined diagnostic error as a diagnosis that is wrong, egregiously delayed, or missed altogether.[6] This is a "label" definition, and can only be applied in retrospect, using some gold standard (for example, autopsy findings or a definitive laboratory test) to confirm the correct diagnosis. Many diagnostic errors fit several of these criteria; the categories overlap.
There are two process-related definitions: Schiff et al. defined diagnostic error as any breakdown in the diagnostic process, including both errors of omission and errors of commission.[7] Similarly, Singh et al. defined diagnostic error as a "missed opportunity" in the diagnostic process, based on retrospective review.[8]
In its landmark report, Improving Diagnosis in Health Care, The National Academy of Medicine proposed a new, hybrid definition that includes both label- and process-related aspects: "A diagnostic error is failure to establish an accurate and timely explanation of the patient's health problem(s) or to communicate that explanation to the patient."[9] This is the only definition that specifically includes the patient in the definition wording.
Definition of prescription error
A prescription or medication error, as defined by the National Coordinating Council for Medication Error Reporting and Prevention, is an event that is preventable that leads to or has led to unsuitable use of medication or has led to harm to the person during the period of time that the medicine is controlled by a clinician, the person, or the consumer.
Impact
Medical errors affect one in 10 patients worldwide.[
UK
In the UK, an estimated 850,000 medical errors occur each year, costing over £2 billion (estimated in the year 2000).[15] The accuracy of this estimate is not clear. Criticism has included the statistical handling of measurement errors in the report,[16] and significant subjectivity in determining which deaths were "avoidable" or due to medical error, and an erroneous assumption that 100% of patients would have survived if optimal care had been provided.[17]
A 2006 study found that medication errors are among the most common medical mistakes, harming at least 1.5 million people every year. According to the study, 400,000 preventable drug-related injuries occur each year in hospitals, 800,000 in long-term care settings, and roughly 530,000 among Medicare recipients in outpatient clinics. The report stated that these are likely to be conservative estimates. In 2000 alone, the extra medical costs incurred by preventable drug-related injuries approximated $887 million—and the study looked only at injuries sustained by Medicare recipients, a subset of clinic visitors. None of these figures take into account lost wages and productivity or other costs.[18]
US
According to a 2002
Cause of death on United States death certificates, statistically compiled by the
Causes
The research literature showed that medical errors are caused by errors of commission and errors of omission.[29] Errors of omission are made when providers did not take action when they should have, while errors of commission occur when decisions and action are delayed.[29] Commission and omission errors have also been attributed with communication failures.[30][31]
Medical errors can be associated with inexperienced physicians and nurses, new procedures, extremes of age, and complex or urgent care.[32] Poor communication (whether in one's own language or, as may be the case for medical tourists, another language), improper documentation, illegible handwriting, spelling errors, inadequate nurse-to-patient ratios, and similarly named medications are also known to contribute to the problem.[33][34] Misdiagnosis may be associated with individual characteristics of the patient or due to the patient multimorbidity.[35][36] Patient actions or inactions may also contribute significantly to medical errors.[31][30]
Healthcare complexity
Complicated technologies,[37][38] powerful drugs, intensive care, rare and multiple diseases,[39] and prolonged hospital stay can contribute to medical errors.[40] In turn, medical errors from carelessness or improper use of medical devices often lead to severe injuries or death. Since 2015, 60 injuries and 23 deaths have been caused by misplaced feeding tubes while using the Cortrak2 EAS system. The FDA recalled Avanos Medical's Cortrak system in 2022 due to its severity and the high toll associated with the medical error.[41]
Complexity makes diagnosis especially challenging. There are less than 200 symptoms listed in Wikipedia,[42] but there are probably more than 10,000 known diseases. The World Health Organization's system for the International Classification of Disease, 9th Edition from 1979 listed over 14,000 diagnosis codes.[43] Textbooks of medicine often describe the most typical presentations of a disease, but in many conditions patients may have variable presentations instead of the classical signs and symptoms. To add complexity, the signs and symptoms of a given condition change over time; in the early stages the signs and symptoms may be absent or minimal, and then these evolve as the condition progresses. Diagnosis is often challenging in infants and children who can't clearly communicate their symptoms, and in the elderly, where signs and symptoms may be muted or absent.[44]
There are more than 7000 rare diseases alone, and in aggregate these are not uncommon: Roughly 1 in 17 patients will be diagnosed with a rare disease over their lifetime.[45] Physicians may have only learned a handful of these during their education and training.
System and process design
In 2000, The Institute of Medicine released "To Err is Human," which asserted that the problem in medical errors is not bad people in health care—it is that good people are working in bad systems that need to be made safer.[20]
Poor communication and unclear lines of authority of physicians, nurses, and other care providers are also contributing factors.[46] Disconnected reporting systems within a hospital can result in fragmented systems in which numerous hand-offs of patients results in lack of coordination and errors.[47]
Other factors include the impression that action is being taken by other groups within the institution, reliance on automated systems to prevent error.,[48] and inadequate systems to share information about errors, which hampers analysis of contributory causes and improvement strategies.[49] Cost-cutting measures by hospitals in response to reimbursement cutbacks can compromise patient safety.[50] In emergencies, patient care may be rendered in areas poorly suited for safe monitoring. The American Institute of Architects has identified concerns for the safe design and construction of health care facilities.[51] Infrastructure failure is also a concern. According to the
The
Competency, education, and training
Variations in healthcare provider training & experience[46][53] and failure to acknowledge the prevalence and seriousness of medical errors also increase the risk.[54][55] The so-called July effect occurs when new residents arrive at teaching hospitals, causing an increase in medication errors according to a study of data from 1979 to 2006.[56][57]
Human factors and ergonomics
Practitioner risk factors include fatigue,[63][64][65] depression,[66] and burnout.[67] Factors related to the clinical setting include diverse patients, unfamiliar settings, time pressures, and increased patient-to-nurse staffing ratio increases.[68] Drug names that look alike or sound alike are also a problem.[69]
Errors in interpreting medical images are often perceptual instead of "fact-based"; these errors are often caused by failures of attention or vision.[70] For example, visual illusions can cause radiologists to misperceive images.[71]
A number of Information Technology (IT) systems have been developed to detect and prevent medication errors, the most common type of medical errors.[72] These systems screen data such as ICD-9 codes, pharmacy and laboratory data. Rules are used to look for changes in medication orders, and abnormal laboratory results that may be indicative of medication errors and/or adverse drug events.[73]
Examples
Errors can include misdiagnosis or delayed diagnosis, administration of the wrong drug to the wrong patient or in the wrong way, giving multiple drugs that interact negatively, surgery on an incorrect site, failure to remove all surgical instruments, failure to take the correct blood type into account, or incorrect record-keeping. A 10th type of error is ones which are not watched for by researchers, such as RNs failing to program an IV pump to give a full dose of IV antibiotics or other medication.
Errors in diagnosis
According to a 2016 study from Johns Hopkins Medicine, medical errors are the third-leading cause of death in the United States.[74] The projected cost of these errors to the U.S. economy is approximately $20 billion, 87% of which are direct increases in medical costs of providing services to patient affected by medical errors.[75] Medical errors can increase average hospital costs by as much as $4,769 per patient.[76] One common type of medical error stems from x-rays and medical imaging: failing to see or notice signs of disease on an image.[70] The retrospective "miss" rate among abnormal imaging studies is reported to be as high as 30% (the real-life error rate is much lower, around 4-5%, because not all images are abnormal),[77] and up to 20% of missed findings result in long-term adverse effects.[78][79]
A large study reported several cases where patients were wrongly told that they were HIV-negative when the physicians erroneously ordered and interpreted HTLV (a closely related virus) testing rather than HIV testing. In the same study, >90% of HTLV tests were ordered erroneously.[80] It is estimated[by whom?] that between 10 and 15% of physician diagnoses are erroneous.[81]
Misdiagnosis of lower extremity cellulitis is estimated to occur in 30% of patients, leading to unnecessary hospitalizations in 85% and unnecessary antibiotic use in 92%. Collectively, these errors lead to between 50,000 and 130,000 unnecessary hospitalizations and between $195 and $515 million in avoidable health care spending annually in the United States.[82]
Misdiagnosis of psychological disorders
Female sexual desire sometimes used to be diagnosed as female hysteria.[citation needed]
Studies have found that
The misdiagnosis of schizophrenia is also a common problem. There may be long delays of patients getting a correct diagnosis of this disorder.[84]
Cluster headaches are often misdiagnosed, mismanaged, or undiagnosed for many years; they may be confused with migraine, "cluster-like" headache (or mimics), CH subtypes, other TACs ( trigeminal autonomic cephalalgias), or other types of primary or secondary headache syndrome.[86] Cluster-like head pain may be diagnosed as secondary headache rather than cluster headache.[87] Under-recognition of CH by health care professionals is reflected in consistent findings in Europe and the United States that the average time to diagnosis is around seven years.[88]
The DSM-5 field trials included "test-retest reliability" which involved different clinicians doing independent evaluations of the same patient—a new approach to the study of diagnostic reliability.[94]
Outpatient vs. inpatient
Misdiagnosis is the leading cause of medical error in outpatient facilities. Since the National Institute of Medicine's 1999 report, "To Err is Human," found up to 98,000 hospital patients die from preventable medical errors in the U.S. each year, government and private sector efforts have focused on inpatient safety.
Medical prescriptions
While in 2000 the Committee on Quality of Health Care in America affirmed medical mistakes are an "unavoidable outcome of learning to practice medicine",
Prescription errors concern ambiguous abbreviations, the right spelling of the full name of drugs: improper use of the nomenclature, of decimal points, unit or rate expressions; legibility and proper instructions; miscalculations of the
Medication errors in hospital include omissions, delayed dosing and incorrect medication administrations. Medication errors are not always readily identified, but can be reported using case note reviews or incident reporting systems.[99] There are pharmacist-led interventions that can reduce the incident of medication error.[100] Electronic prescribing has been shown to reduce prescribing errors by up to 30%.[101]
Mitigation (after an error)
Mistakes can have a strongly negative emotional impact on the doctors who commit them.[102][103][104][105]
Recognizing that mistakes are not isolated events
Some physicians recognize that adverse outcomes from errors usually do not happen because of an isolated error and actually reflect system problems.
There may be several breakdowns in processes to allow one adverse outcome.[108] In addition, errors are more common when other demands compete for a physician's attention.[109][110][111] However, placing too much blame on the system may not be constructive.[53]
Placing the practice of medicine in perspective
Essayists imply that the potential to make mistakes is part of what makes being a physician rewarding and without this potential the rewards of medical practice would be diminished. Laurence states that "Everybody dies, you and all of your patients. All relationships end. Would you want it any other way? [...] Don't take it personally".[112] Seder states "[...] if I left medicine, I would mourn its loss as I've mourned the passage of my poetry. On a daily basis, it is both a privilege and a joy to have the trust of patients and their families and the camaraderie of peers. There is no challenge to make your blood race like that of a difficult case, no mind game as rigorous as the challenging differential diagnosis, and though the stakes are high, so are the rewards."[113]
Disclosing mistakes
Forgiveness, which is part of many cultural traditions, may be important in coping with medical mistakes.[114] Among other healing processes, it can be accomplished through the use of communicative disclosure guidelines.[115]
To oneself
Inability to forgive oneself may create a cycle of distress and increased likelihood of a future error.[116]
However, Wu et al. suggest "...those who coped by accepting responsibility were more likely to make constructive changes in practice, but [also] to experience more emotional distress."[117] It may be helpful to consider the much larger number of patients who are not exposed to mistakes and are helped by medical care.[113]
To patients
Gallagher et al. state that patients want "information about what happened, why the error happened, how the error's consequences will be mitigated, and how recurrences will be prevented."[118] Interviews with patients and families reported in a 2003 book by Rosemary Gibson and Janardan Prasad Singh, put forward that those who have been harmed by medical errors face a "wall of silence" and "want an acknowledgement" of the harm.[119] With honesty, "healing can begin not just for the patients and their families but also the doctors, nurses and others involved." In a line of experimental investigations, Annegret Hannawa et al. developed evidence-based disclosure guidelines under the scientific "Medical Error Disclosure Competence (MEDC)" framework.[115][120]
A review of studies examining patients' views on investigations of medical harm found commonalities in their expectations of the process. For example, many wanted reviews to be transparent, trustworthy, and person-centred to meet their needs. People wanted to be meaningfully involved in the process and to be treated with respect and empathy. Justice-seekers wanted an honest account of what happened, the circumstances leading up to it, and measures to ensure it does not happen again. Processes that, for example, involved people independent of the organisation responsible for harm gave investigations credibility.[121][122]
A 2005 study by Wendy Levinson of the University of Toronto showed surgeons discussing medical errors used the word "error" or "mistake" in only 57 percent of disclosure conversations and offered a verbal apology only 47 percent of the time.[123]
Patient disclosure is important in the medical error process. The current standard of practice at many hospitals is to disclose errors to patients when they occur. In the past, it was a common fear that disclosure to the patient would incite a malpractice lawsuit. Many physicians would not explain that an error had taken place, causing a lack of trust toward the healthcare community. In 2007, 34 states passed legislation that precludes any information from a physician's apology for a medical error from being used in malpractice court (even a full admission of fault).[124] This encourages physicians to acknowledge and explain mistakes to patients, keeping an open line of communication.
The American Medical Association's Council on Ethical and Judicial Affairs states in its ethics code:
- "Situations occasionally occur in which a patient suffers significant medical complicationsthat may have resulted from the physician's mistake or judgment. In these situations, the physician is ethically required to inform the patient of all facts necessary to ensure understanding of what has occurred. Concern regarding legal liability which might result following truthful disclosure should not affect the physician's honesty with a patient."
From the American College of Physicians Ethics Manual:[125]
- "In addition, physicians should disclose to patients information about procedural or judgment errors made in the course of care if such information is material to the patient's well-being. Errors do not necessarily constitute improper, negligent, or unethical behavior, but failure to disclose them may."
However, "there appears to be a gap between physicians' attitudes and practices regarding error disclosure. Willingness to disclose errors was associated with higher training level and a variety of patient-centered attitudes, and it was not lessened by previous exposure to malpractice litigation".[126] Hospital administrators may share these concerns.[127]
Consequently, in the United States, many states have enacted laws excluding expressions of sympathy after accidents as proof of liability.
Disclosure may actually reduce malpractice payments.[128][129]
To non-physicians
In a study of physicians who reported having made a mistake, it was offered that disclosing to non-physician sources of support may reduce stress more than disclosing to physician colleagues.[130] This may be due to the finding that of the physicians in the same study, when presented with a hypothetical scenario of a mistake made by another colleague, only 32% of them would have unconditionally offered support. It is possible that greater benefit occurs when spouses are physicians.[131]
To other physicians
Discussing mistakes with other physicians is beneficial.[53] However, medical providers may be less forgiving of one another.[131] The reason is not clear, but one essayist has admonished, "Don't Take Too Much Joy in the Mistakes of Other Doctors."[132]
To the physician's institution
Disclosure of errors, especially "near misses", may be able to reduce subsequent errors in institutions that are capable of reviewing near misses.[133] However, doctors report that institutions may not be supportive of the doctor.[53]
Use of rationalization to cover up medical errors
Based on anecdotal and survey evidence, Banja
By potential for harm to the patient
In a survey of more than 10,000 physicians in the United States, when asked the question, "Are there times when it's acceptable to cover up or avoid revealing a mistake if that mistake would not cause harm to the patient?", 19% answered yes, 60% answered no and 21% answered it depends. On the question, "Are there times when it is acceptable to cover up or avoid revealing a mistake if that mistake would potentially or likely harm the patient?", 2% answered yes, 95% answered no and 3% answered it depends.[135]
Legal procedure
Standards and regulations for medical malpractice vary by country and jurisdiction within countries. Medical professionals may obtain professional liability insurances to offset the risk and costs of lawsuits based on medical malpractice.
Prevention
Medical care is frequently compared adversely to aviation; while many of the factors that lead to errors in both fields are similar, aviation's error management protocols are regarded as much more effective.[136] Safety measures include informed consent, the availability of a second practitioner's opinion, voluntary reporting of errors, root cause analysis, reminders to improve patient medication adherence, hospital accreditation, and systems to ensure review by experienced or specialist practitioners.[137]
A template has been developed for the design (both structure and operation) of hospital medication safety programmes, particularly for acute tertiary settings,[138] which emphasizes safety culture, infrastructure, data (error detection and analysis), communication and training.
Particularly to prevent the medication errors in the perspective of the intrathecal administration of local anaesthetics, there is a proposal to change the presentation and packaging of the appliances and agents used for this purpose. One spinal needle with a syringe prefilled with the local anaesthetic agents may be marketed in a single blister pack, which will be peeled open and presented before the anaesthesiologist conducting the procedure.[139]
Physician well-being has also been recommended as an indicator of healthcare quality given its association with patient safety outcomes.[140] A meta-analysis involving 21517 participants found that physicians with depressive symptoms had a 95% higher risk of reporting medical errors and that the association between physician depressive symptoms and medical errors is bidirectional [66]
Reporting requirements
In the United States, adverse medical event reporting systems were mandated in just over half (27) of the states as of 2014, a figure unchanged since 2007.[141][142] In U.S. hospitals error reporting is a condition of payment by Medicare.[143] An investigation by the Office of Inspector General, Department of Health and Human Services released January 6, 2012 found that most errors are not reported and even in the case of errors that are reported and investigated changes are seldom made which would prevent them in the future. The investigation revealed that there was often lack of knowledge regarding which events were reportable and recommended that lists of reportable events be developed.[144]
Cause-specific preventive measures
Traditionally, errors are attributed to mistakes made by individuals, who then may be penalized. A common approach to respond to and prevent specific errors is requiring additional checks at particular points in the system, whose findings and detail of execution must be recorded. As an example, an error of free flow IV administration of heparin is approached by teaching staff how to use the IV systems and to use special care in setting the IV pump. While overall errors become less likely, the checks add to workload and may in themselves be a cause of additional errors. In some hospitals, a regular morbidity and mortality conference meeting is scheduled to discuss complications or deaths and learn from or improve the overall processes.
A newer model for improvement in medical care takes its origin from the work of
Anaesthesiology
The field of medicine that has taken the lead in systems approaches to safety is
Medications
Reducing errors in prescribing, dispensing, compounding/formulating, labelling, and handling medications is a priority and has been the subject of systematic reviews and studies. Examples of areas to reduce medication errors and improve safety include: Training professionals or using databases to compare new and previous prescribed medications to prevent mistakes, also known as "
Historically
As far back as the 1930s, pharmacists worked with physicians to select, from many options, the safest and most effective drugs available for use in hospitals.
Misconceptions
Some common misconceptions about medical error include:
- Medical error is the "third leading cause of death" in the United States. This canard stems from an erroneous 2016 study which, according to David Gorski, "has taken on a life of its own" and fuelled "a myth promulgated by both quacks and academics".[153]
- "Bad apples" or incompetent health care providers are a common cause. (Although human error is commonly an initiating event, the faulty care delivery process invariably permits or compounds the harm and so is the focus of improvement.)[22]
- High-risk procedures or medical specialties are responsible for most avoidable adverse events. (Although some mistakes, such as in surgery, are harder to conceal, errors occur in all levels of care.[22] Even though complex procedures entail more risk, adverse outcomes are not usually due to error, but to the severity of the condition being treated.)[46][154] However, United States Pharmacopeia has reported that medication errors during the course of a surgical procedure are three times more likely to cause harm to a patient than those occurring in other types of hospital care.[47]
- If a patient experiences an adverse event during the process of care, an error has occurred. (Most medical care entails some level of risk, and there can be complications or side effects, even unforeseen ones, from the underlying condition or from the treatment itself.)[20]
See also
- Serious adverse event
- Adverse drug reaction
- Biosafety
- Emily's Law
- Fatal Care: Survive in the U.S. Health System(book)
- Medical malpractice
- Medical resident work hours
- Sleep deprivation
- Patient Safety and Quality Improvement Act of 2005
- Patient safety organization
- Quality Use of Medicines
References
- PMID 12386188.
- S2CID 18663388.
- PMID 11151522. Archived from the originalon September 28, 2007. Retrieved June 11, 2007.
- PMID 11466119.
- PMID 17095810.
- ^ Graber ML, Franklin N, Gordon R. Diagnostic error in internal medicine. Arch Intern Med. 2005;165(13):1493-1499.
- ^ Schiff GD, Hasan O, Kim S, et al. Diagnostic Error in Medicine - Analysis of 583 Physician-Reported Errors. Arch Int Med. 2009;169(20):1881-1887.
- ^ Singh H. Helping health care organizations to define diagnostic errors as missed opportunities in diagnosis. Joint Commission Journal on Quality and Patient Safety. 2014;40(3):99-101.
- ^ Institute of Medicine. Improving Diagnosis in Health Care. National Academies Press, Washington, DC. 2015.
- ^ "Medication Error Definition". National Coordinating Council for Medication Error Reporting and Prevention. Retrieved July 17, 2023.
- ^ PMID 34822165.
- PMID 7503827.
- ^ "Cancer". World Health Organization. Retrieved March 2, 2017.
- ^ PMID 25756542.
- ^ Donaldson, L (2000). "An organisation with a memory: Report of an expert group on learning from adverse events in the NHS". Patient Safety Network, UK. Retrieved July 17, 2023.
- PMID 17610445.
- ^ PMID 11466119.
- ^ "Medication Errors Injure 1.5 Million People and Cost Billions of Dollars Annually". The National Academy of Science. 2006.
- The Commonwealth Fund
- ^ PMID 25077248.
- PMID 10698861.
- ^ PMID 10720365.
- ^ S2CID 3101439.
- ^ PMID 15109337.
- PMID 12826639.
- PMID 14573739.
- S2CID 206910205.
- ISBN 978-0-8406-0644-0.
- ^ PMID 31509277.
- ^ ISBN 978-3-11-045485-7.
- ^ ISBN 978-3-11-045501-4.
- PMID 10720365.
- ^ Friedman, Richard A.; D, M (2003). "CASES; Do Spelling and Penmanship Count? In Medicine, You Bet". The New York Times. Retrieved August 29, 2018.
- S2CID 169364817.
- S2CID 240154096.
- PMID 32819954.
- PMID 30457880.
- PMID 18628322.
- S2CID 53758271.
- PMID 10854389.
- ^ "Feeding Tube Placement Devices Recalled After 23 Patient Deaths". schmidtlaw.com.
- ^ List of medical symptoms. https://en.wikipedia.org/wiki/List_of_medical_symptoms#Medical_signs_and_symptoms
- ^ Utter,GH; Atolagbe, OO; Cooke, DT. The Use of the International Classification of Diseases, Tenth Revision, Clinical Modification and Procedure Classification System in Clinical and Health Services Research; The Devil Is in the Details. JAMA Surgery. 2019;154(12):1089-1090
- ^ Emmett, KR. Nonspecific and atypical presentation of disease in the older patient. Geriatrics. 1998; 53(2):50–52
- ^ Ronicke, S; Hirsch, MC; Türk, E; Larionov, K; Tientcheu1, D; Wagne, AD. Can a decision support system accelerate rare disease diagnosis? Evaluating the potential impact of Ada DX in a retrospective study. Orphanet Journal of Rare Diseases. 2019. 14:69
- ^ PMID 11418700.
- ^ a b Gardner, Amanda (March 6, 2007). "Medication Errors During Surgeries Particularly Dangerous". The Washington Post. Retrieved March 13, 2007.
- PMID 16585665.
- ^ US Agency for Healthcare Research & Quality (January 9, 2008). "Physicians Want To Learn from Medical Mistakes but Say Current Error-reporting Systems Are Inadequate". Archived from the original on February 17, 2008. Retrieved March 23, 2008.
- S2CID 22206854.
- ^ "Incorporating Patient-Safe Design into the Guidelines". The American Institute of Architects Academy Journal. October 19, 2005.
- ^ The Joint Commission's Annual Report on Quality and Safety 2007: Improving America's Hospitals (Accessed 2008-04-09)
- ^ PMID 2013929.
- S2CID 40037135.
- PMID 17901458. Retrieved March 23, 2008.
- PMID 20512532.
- ^ Krupa, Carolyne (June 21, 2010). "New residents linked to July medication errors". American Medical News. 6 (21).
- New York Review of Books.
- PMID 19638766.
- ^ PMID 20464765.
- PMID 17194188.
- ^ a b When Doctors Don't Sleep, Talk of the Nation, National Public Radio, 13 December 2006.
- S2CID 34759813.
- PMID 15509817.
- PMID 17194188.
- ^ PMID 31774520.
- PMID 18258931.
- PMID 12387650.
- U.S. Pharmacopeia. Archived from the original on February 8, 2008. Retrieved March 23, 2008.)
{{cite web}}
: CS1 maint: numeric names: authors list (link - ^ PMID 31293407.
- PMID 34177444.
- ^ Anderson, J.G. (2005). Information technology for detecting medication errors and adverse drug events. (Expert Opin Drug Saf 3). pp. 449–455.
- PMID 28186008.
- S2CID 206910205.
- ^ Shreve, J et al (Milliman Inc.) (June 2010). "The Economic Measurement of Medical Errors" (PDF). Society of Actuaries.
- SSRN 2262792.
- PMID 17449754.
- PMID 27928712.
- PMID 23536732.
- PMID 23173397.
- PMID 18440350.
- S2CID 205110504.
- PMID 11141528.
- ^ "Schizophrenia Symptoms". schizophrenia.com. Retrieved March 30, 2008.
- PMID 16292119.
- PMID 12876249.
- ^ "IHS Classification ICHD-II 3.1 Cluster headache". The International Headache Society. Archived from the original on 3 November 2013. Retrieved 3 January 2014.
- S2CID 22522914.
- PMID 27032954.
- S2CID 25077268.
- S2CID 43475267.
- .
- S2CID 26112061.
- ^ "Reliability and Prevalence in the DSM-5 Field Trials" (PDF). January 12, 2012. Archived from the original (PDF) on January 31, 2012. Retrieved January 13, 2012.
- PMID 25077248.
- ^ OCLC 8186593909. Archived from the original on September 26, 2020 – via DOAJ.)
{{cite journal}}
: External link in
(help|via=
- ^ "APPEAL NO. 991681 Texas v. Dr. K" (PDF). Retrieved April 16, 2020.
- ^ Elliott, Rachel (February 22, 2018). "PREVALENCE AND ECONOMIC BURDEN OF MEDICATION ERRORS IN THE NHS IN ENGLAND" (PDF). University of Sheffield. Policy Research Unit in Economic Evaluation of Health & Care Interventions. Retrieved June 19, 2022.
- ^ https://academic.oup.com/ijpp/article/28/6/663/6133310?login=false.
{{cite web}}
: Missing or empty|title=
(help) - S2CID 229332634.
- PMID 17662088.
- PMID 6690918.
- S2CID 415258.
- PMID 10720336.
- PMID 17724943.
- ^ PMID 11101708.
- ^ a b c Romero-Perez, Raquel; Hildick-Smith, Philippa (September 2012). "Minimising Prescribing Errors in Paediatrics - Clinical Audit" (PDF). Scottish Universities Medical Journal. 1: 14–1.
- S2CID 29006252.
- PMID 9593791.
- PMID 2725617.
- PMID 1275366.
- ISBN 978-1-56053-603-1.
- ^ S2CID 2927435.
- PMID 15681676.
- ^ a b "Medical Error Disclosure Competence (MEDC) -- Prof. Dr. Annegret Hannawa". prof. annegret hannawa. Retrieved April 21, 2021.
- PMID 16954486.
- PMID 8279153.
- PMID 12597752.
- ISBN 978-0-89526-112-0.
- PMID 9436897.
- PMID 37452516.
- S2CID 266946352.
- ^ Kelly, Karen (2005). "Study explores how physicians communicate mistakes". University of Toronto. Archived from the original on March 22, 2006. Retrieved March 17, 2006.
- ^ Agency for Healthcare Research and Quality (AHRQ) http://psnet.ahrq.gov/primer.aspx?primerID=2
- S2CID 53090205.
- PMID 17473944.
- PMID 15769969.
- S2CID 36889006.
- ^ Zimmerman R (May 18, 2004). "Doctors' New Tool To Fight Lawsuits: Saying 'I'm Sorry'". The Wall Street Journal. p. A1. Archived from the original on August 23, 2007.
- PMID 8601210.
- ^ PMID 10068390.
- ISBN 978-0-89815-197-8.
- PMID 10720361.
- ISBN 978-0-7637-8361-7.
- ^ Weiss, Gail Garfinkel (January 4, 2011). "'Some Worms Are Best Left in the Can' -- Should You Hide Medical Errors?". Medscape.
- PMID 10720367.
- PMID 10720354.
- S2CID 54178056.
- PMID 27512177.
- PMID 26921157.
- ^ Hanlon, Carrie; Sheedy, Kaitlin; Kniffin, Taylor; Rosenthal, Jill (2015). "2014 Guide to State Adverse Event Reporting Systems" (PDF). NASHP.org. National Academy for State Health Policy. Retrieved April 22, 2016.
- PMID 19388488. Retrieved April 22, 2016.
- ^ "Report Finds Most Errors at Hospitals Go Unreported" article by Robert Pear in The New York Times January 6, 2012
- ^ Summary "Hospital Incident Reporting Systems Do Not Capture Most Patient Harm" Report (OEI-06-09-00091) Office of Inspector General, Department of Health and Human Services, January 6, 2012
- PMID 10720368.
- PMID 21328749, retrieved July 17, 2023
- PMID 28977687.
- ^ Pease E (1936). "Minimum standards for a hospital pharmacy". Bull Am Coll Surg. 21: 34–35.
- )
- )
- )
- )
- ^ Gorski DH (February 4, 2019). "Are medical errors really the third most common cause of death in the U.S.? (2019 edition)". Science-Based Medicine.
- PMID 15867408.
Further reading
- ISBN 978-0-8050-6319-6.
- Wachter, Robert; Shojania, Kaveh (2004). Internal Bleeding: The Truth Behind America's Terrifying Epidemic of Medical Mistakes. New York: Rugged Land. ISBN 978-1-59071-016-6.
- Banja, John (2005). ISBN 978-0-7637-8361-7.
- Porter, Michael E.; Olmsted Teisberg, Elizabeth (2006). Redefining Health Care: Creating Value-Based Competition on Results. Boston: Harvard Business School Press. ISBN 978-1-59139-778-6.
- Gibson, Rosemary; Prasad Singh, Janardan (2003). Wall of Silence: The Untold Story of the Medical Mistakes That Kill and Injure Millions of Americans. Washington D.C.: Regnery. ISBN 978-0-89526-112-0.
- Alldred D.P.; Standage C.; Zermansky A.G.; Jesson B.; Savage I.; Franklin B.D.; Barber N.; Raynor D.K. (2008). "Development and validation of criteria to identify medication-monitoring errors in care home residents". International Journal of Pharmacy Practice. 16 (5): 317–323. S2CID 71701489.
- Committee on Identifying and Preventing Medication Errors; Board on Health Care Services (2007). Preventing medication errors. National Academies Press. ISBN 978-0-309-10147-9.
- Tewari, A.; Palm, B.; Hines, T.; Royer, T.; Alexander, E. (2014). "VEINROM: A possible solution for erroneous intravenous drug administration". Journal of Anaesthesiology Clinical Pharmacology. 30 (2): 263–266. PMID 24803770.