Monobenzone
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| Clinical data | |
|---|---|
| Other names | Hydroquinone benzyl ether, Hydroquinone monobenzyl ether, Benzyl p-hydroxyphenyl ether, Benzyl hydroquinone, Benzoquin, 4-(phenylmethoxy)phenol |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Topical |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
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ECHA InfoCard | 100.002.804 |
| Chemical and physical data | |
| Formula | C13H12O2 |
| Molar mass | 200.237 g·mol−1 |
  (what is this?) (verify) | |
Monobenzone, also called 4-(Benzyloxy)phenol and monobenzyl ether of hydroquinone (MBEH) is an
topical drug for medical depigmentation.[3] It is a colourless solid that is classified as the monobenzyl ether of hydroquinone. Monobenzone is soluble in alcohol, benzene, and diethyl ether, and practically insoluble in water
.
Pharmacology
The topical application of monobenzone in animals increases the excretion of
melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation. [citation needed
]
The
References
- ^ "4-(Benzyloxy)phenol - Substance Summary". PubChem. U.S. National Library of Medicine. Retrieved 9 September 2013.
- ^ "4-(Benzyloxy)phenol, 98%". ChemExper. Retrieved 9 September 2013.
- ^ "Monobenzone topical". eMedicineHealth. WebMD, Inc. Archived from the original on 22 March 2017.
- ^ "Monobenzone as Immunotherapy for Melanoma". jwatch. Archived from the original on 2013-01-01. Retrieved 2012-06-26.
Further reading
- Bolognia JL, Lapia K, Somma S (January 2001). "Depigmentation therapy. Dermatologic Therapy". 14 (1): 29–34. )
External links
- "Monobenzone". Drug Information Portal. U.S. National Library of Medicine.