Myoepithelial cell
Myoepithelial cell | |
---|---|
Details | |
Identifiers | |
Latin | myoepitheliocytus |
TH | H2.00.02.0.03059 |
FMA | 67799 67805, 67799 |
Anatomical terminology |
Myoepithelial cells (sometimes referred to as myoepithelium) are cells usually found in
malignant
components.
It can be found in endoderm or ectoderm.[1]
Markers
Myoepithelial cells are true
p63 and caldesmon
.
Myoepithelial cells are stellate in shape and are also known as basket cells.
They lie between the basement membrane and glandular epithelium.
Each cell consists of a cell body from which 4-8 processes radiate and embrace the secretory unit. Myoepithelial cells have contractile functions. They help in expelling secretions from the lumen of secretory units and facilitate the movement of saliva in salivary ducts.
Other Cancers Involving This Type of Cell
- Myoepithelioma of the head and neck - A (usually) benign tumor of the head/neck consisting of solely myoepithelial cells.
- Epithelial-myoepithelial carcinoma (of the salivary glands) - A low-grade malignant tumor composed of both neoplastic epithelial and neoplastic myoepithelial cells (a biphasic tumor).
- Epithelial-myoepithelial carcinoma of the lung- A malignant tumor composed of both epithelial and myoepithelial tissues whose pathology resemble salivary cells.
- Adeno(glandular) cells.
- Myoepithelioma of the Breast- A usually benign or exceedingly rare malignant tumor of the breast which mimics IDC but with cells resembling adenoid cysts. If malignant, this is also known as a Myoepithelial Carcinoma.
See also
List of distinct cell types in the adult human body
References
- ISBN 978-0-7637-5570-6. Retrieved 16 April 2010.
External links
- Anatomy Atlases – Microscopic Anatomy, plate 07.141 - "Axillary Sweat Gland: Myoepithelium"
- Histology image: 43_13 at the University of Oklahoma Health Sciences Center - "thick skin"
- Histology at KUMC glands-glands09 "Simple Tubular Coiled"
- Costoff, A., Essentials of Human Physiology, archived from the original on 2015-11-20
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